Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles

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dc.identifier.uri http://dx.doi.org/10.15488/3499
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/3529
dc.contributor.author Gittard, Shaun D.
dc.contributor.author Miller, Philip R.
dc.contributor.author Boehm, Ryan D.
dc.contributor.author Ovsianikov, Aleksandr
dc.contributor.author Chichkov, Boris
dc.contributor.author Heiser, Jeremy
dc.contributor.author Gordon, John
dc.contributor.author Monteiro-Riviere, Nancy A.
dc.contributor.author Narayan, Roger J.
dc.date.accessioned 2018-06-27T11:45:30Z
dc.date.available 2018-06-27T11:45:30Z
dc.date.issued 2011
dc.identifier.citation Gittard, S.D.; Miller, P.R.; Boehm, R.D.; Ovsianikov, A.; Chichkov, B.N. et al.: Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles. In: Faraday Discussions 149 (2011), S. 171-185. DOI: https://doi.org/10.1039/c005374k
dc.description.abstract Due to their ability to serve as fluorophores and drug delivery vehicles, quantum dots are a powerful tool for theranostics-based clinical applications. In this study, microneedle devices for transdermal drug delivery were fabricated by means of two-photon polymerization of an acrylate-based polymer. We examined proliferation of cells on this polymer using neonatal human epidermal keratinocytes and human dermal fibroblasts. The microneedle device was used to inject quantum dots into porcine skin; imaging of the quantum dots was performed using multiphoton microscopy. © 2011 The Royal Society of Chemistry. eng
dc.language.iso eng
dc.publisher Cambridge : Royal Society of Chemistry
dc.relation.ispartofseries Faraday Discussions 149 (2011)
dc.rights Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. ger
dc.subject polymer eng
dc.subject quantum dot eng
dc.subject animal eng
dc.subject article eng
dc.subject chemistry eng
dc.subject cytology eng
dc.subject drug delivery system eng
dc.subject female eng
dc.subject fluorescence microscopy eng
dc.subject human eng
dc.subject instrumentation eng
dc.subject intradermal drug administration eng
dc.subject keratinocyte eng
dc.subject methodology eng
dc.subject microinjection eng
dc.subject needle eng
dc.subject newborn eng
dc.subject skin eng
dc.subject swine eng
dc.subject Administration, Cutaneous eng
dc.subject Animals eng
dc.subject Drug Delivery Systems eng
dc.subject Female eng
dc.subject Humans eng
dc.subject Infant, Newborn eng
dc.subject Keratinocytes eng
dc.subject Microinjections eng
dc.subject Microscopy, Fluorescence eng
dc.subject Needles eng
dc.subject Polymers eng
dc.subject Quantum Dots eng
dc.subject Skin eng
dc.subject Swine eng
dc.subject.ddc 540 | Chemie ger
dc.title Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles
dc.type Article
dc.type Text
dc.relation.issn 1359-6640
dc.relation.doi https://doi.org/10.1039/c005374k
dc.bibliographicCitation.volume 149
dc.bibliographicCitation.firstPage 171
dc.bibliographicCitation.lastPage 185
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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