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A computational model for previtamin D 3 production in skin

Meinhardt-Wollweber, Merve; Krebs, Ronald (Cambridge : Royal Society of Chemistry, 2012)

Low levels of vitamin D have been implicated in a wide variety of health issues from calcemic diseases to cancer, diabetes and cardiovascular disease. For most humans, the majority of vitamin D 3 is derived from sunlight. ...
Abdominal obesity‐related disturbance of insulin sensitivity is associated with cd8+ emra cells in the elderly

Boßlau, Tim K.; Wasserfurth, Paulina; Krüger, Britta; Reichel, Thoma; Palmowski, Jana; Nebl, Josefine; Weyh, Christopher; Schenk, Alexander; Joisten, Niklas; Stahl, Frank; Thoms, Stefanie; Gebhardt, Kristina; Hahn, Andreas; Krüger, Karsten (Basel : MDPI, 2021)

Aging and overweight increase the risk of developing type 2 diabetes mellitus. In this cross‐sectional study, we aimed to investigate the potential mediating role of T‐EMRA cells and inflammatory markers in the development ...
The acquisition of plural marking in English and German revisited: Schemata versus rules

Köpcke, Klaus-Michael (Cambridge : Cambridge University Press, 1998)

[No abstract available]
Adhesion, Vitality and Osteogenic Differentiation Capacity of Adipose Derived Stem Cells Seeded on Nitinol Nanoparticle Coatings

Strauß, Sarah; Neumeister, Anne; Barcikowski, Stephan; Kracht, Dietmar; Kuhbier, Jörn W.; Radtke, Christine; Reimers, Kerstin; Vogt, Peter M. (San Francisco, California, US : PLOS, 2013)

Autologous cells can be used for a bioactivation of osteoimplants to enhance osseointegration. In this regard, adipose derived stem cells (ASCs) offer interesting perspectives in implantology because they are fast and easy ...
An unusual overrepresentation of genetic factors related to iron homeostasis in the genome of the fluorescent Pseudomonas sp. ABC1

Valenzuela-Heredia, Daniel; Henríquez-Castillo, Carlos; Donoso, Raúl; Lavín, Paris; Ringel, Michael T.; Brüser, Thomas; Campos, José Luis (Oxford : Wiley-Blackwell, 2021)

Members of the genus Pseudomonas inhabit diverse environments, such as soil, water, plants and humans. The variability of habitats is reflected in the diversity of the structure and composition of their genomes. This ...
Are multiple contrast tests superior to the ANOVA?

Konietschke, Frank; Bösiger, Sandra; Brunner, Edgar; Hothorn, Ludwig A. (Berlin : Walter de Gruyter, 2013)

Multiple contrast tests can be used to test arbitrary linear hypotheses by providing local and global test decisions as well as simultaneous confidence intervals. The ANOVA-F-test on the contrary can be used to test the ...
Assessment of the effectiveness of the post-Fukushima food monitoring campaign in the first year after the nuclear accident: A hypothesis

Steinhauser, Georg (London : Elsevier Ltd, 2016)

The purpose of this study was to assess whether or not the food monitoring campaign after the Fukushima nuclear accident has been successful in reducing the number of above-limit-food from reaching the consumers. The ...
Binding of a Pyrene-Based Fluorescent Amyloid Ligand to Transthyretin: A Combined Crystallographic and Molecular Dynamics Study

Thi Minh, Nghia Nguyen; Begum, Afshan; Zhang, Jun; Leira, Petter; Todarwal, Yogesh; Linares, Mathieu; Norman, Patrick; Derbyshire, Dean; von Castelmur, Eleonore; Lindgren, Mikael; Hammarström, Per; König, Carolin (Washington, DC : Soc., 2023)

Misfolding and aggregation of transthyretin (TTR) cause several amyloid diseases. Besides being an amyloidogenic protein, TTR has an affinity for bicyclic small-molecule ligands in its thyroxine (T4) binding site. One class ...
CEDAR, an online resource for the reporting and exploration of complexome profiling data

van Strien, Joeri; Haupt, Alexander S.; Schulte, Uwe; Braun, Hans-Peter; Cabrera-Orefice, Alfredo; Choudhary, Jyoti S.; Evers, Felix; Fernandez-Vizarra, Erika; Guerrero-Castillo, Sergio; Kooij, Taco W.A.; Páleníková, Petra; Pardo, Mercedes; Ugalde, Cristina; Wittig, Ilka; Wöhlbrand, Lars; Brandt, Ulrich; Arnold, Susanne; Huynen, Martijn A. (Amsterdam : Elsevier, 2021)

Complexome profiling is an emerging ‘omics’ approach that systematically interrogates the composition of protein complexes (the complexome) of a sample, by combining biochemical separation of native protein complexes with ...
... a certain amount of engineering involved: Constructing the public in participatory governance arrangements

Braun, Kathrin; Schultz, Susanne (London : SAGE Publications Ltd., 2010)

This paper argues that it is time for public understanding of science to develop a critical inventory of the forms, formats and methods of public participation and their respective implications and ambiguities. It highlights ...
Citizen science project characteristics: Connection to participants' gains in knowledge and skills

Peter, Maria; Diekötter, Tim; Kremer, Kerstin; Höffler, Tim (San Francisco, California, US : PLOS, 2021)

Background: Biodiversity is being lost rapidly and its conservation is thus one of the most urgent tasks today. For biodiversity conservation to be successful, the public needs to gain an awareness and understanding of ...
Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism

Hartleben, Goetz; Schorpp, Kenji; Kwon, Yun; Betz, Barbara; Tsokanos, Foivos-Filippos; Dantes, Zahra; Schäfer, Arlett; Rothenaigner, Ina; Monroy Kuhn, José Manuel; Morigny, Pauline; Mehr, Lisa; Lin, Sean; Seitz, Susanne; Tokarz, Janina; Artati, Anna; Adamsky, Jerzy; Plettenburg, Oliver; Lutter, Dominik; Irmler, Martin; Beckers, Johannes; Reichert, Maximilian; Hadian, Kamyar; Zeigerer, Anja; Herzig, Stephan; Berriel Diaz, Mauricio (Weinheim : Wiley-VCH, 2021)

By accentuating drug efficacy and impeding resistance mechanisms, combinatorial, multi-agent therapies have emerged as key approaches in the treatment of complex diseases, most notably cancer. Using high-throughput drug ...
Comparative in vitro study and biomechanical testing of two different magnesium alloys

Weizbauer, Andreas; Modrejewski, Christian; Behrens, Sabine; Klein, Helmut; Helmecke, Patrick; Seitz, Jan-Marten; Windhagen, Henning; Möhwald, Kai; Reifenrath, Janin; Waizy, Hazibullah (London : SAGE Publications Ltd., 2014)

In this in vitro study, magnesium plates of ZEK100 and MgCa0.8 alloy similar to common titanium alloy osteosynthesis plates were investigated as degradable biomedical materials with a focus on primary stability. Immersion ...
Comparison of nanoparticle-mediated transfection methods for DNA expression plasmids: Efficiency and cytotoxicity

Durán, Maria Carolina; Willenbrock, Saskia; Barchanski, Annette; Müller, Jessika-M.V.; Maiolini, Arianna; Soller, Jan T.; Barcikowski, Stephan; Nolte, Ingo; Feige, Karsten; Murua Escobar, Hugo (London : Biomed Central, 2011)

Background: Reproducibly high transfection rates with low methodology-induced cytotoxic side effects are essential to attain the required effect on targeted cells when exogenous DNA is transfected. Different approaches and ...
Comparison of plasma responses human subjects after the ingestion of 3R,3R′-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R′-zeaxanthin using chiral high-performance liquid chromatography

Breithaupt, Dietmar E.; Weller, Philipp; Wolters, Maike; Hahn, Andreas (Cambridge : Cambridge University Press, 2004)

Age-related macular degeneration (AMD) is one of the most common eye diseases of elderly individuals. It has been suggested that lutein and zeaxanthin may reduce the risk for AMD. Information concerning the absorption of ...
Computational model of damage-induced growth in soft biological tissues considering the mechanobiology of healing

Gierig, Meike; Wriggers, Peter; Marino, Michele (Berlin ; Heidelberg ; New York, NY : Springer, 2021)

Healing in soft biological tissues is a chain of events on different time and length scales. This work presents a computational framework to capture and couple important mechanical, chemical and biological aspects of ...
Consent for Biobanking: The Legal Frameworks of Countries in the BioSHaRE-EU Project

Kaye, Jane; Briceño Moraia, Linda; Curren, Liam; Bell, Jessica; Mitchell, Colin; Soini, Sirpa; Hoppe, Nils; Øien, Morten; Rial-Sebbag, Emmanuelle (New Rochelle, NY : Liebert, 2016)

Currently, there is no single, Europe-wide regulation of biomedical research using human samples and data. Instead, the law that applies spans a number of areas of law, such as data protection, clinical trials, and tissue ...
Contrast-enhanced nano-CT reveals soft dental tissues and cellular layers

Hildebrand, T.; Nogueira, L.; Sunde, P.T.; Ørstavik, D.; Glasmacher, B.; Haugen, H.J. (Oxford [u.a.] : Wiley-Blackwell, 2021)

Aim: To introduce a methodology designed to simultaneously visualize dental ultrastructures, including cellular and soft tissue components, by utilizing phosphotungstic acid (PTA) as a contrast-enhancement agent. Methodology: ...
Cost effectiveness of ulcerative colitis treatment in Germany: A comparison of two oral formulations of mesalazine

Prenzler, Anne; Yen, Linnette; Mittendorf, Thomas; Schulenburg, Johann-Matthias Graf von der (London : BioMed Central Ltd., 2011)

Background: The treatment of ulcerative colitis (UC) can place a substantial financial burden on healthcare systems. The anti-inflammatory compound 5-aminosalicylic acid (5-ASA; mesalazine) is the recommended first-line ...
Cost-effectiveness of primarily human papillomavirus-based cervical cancer screening in settings with currently established Pap screening: A systematic review commissioned by the German Federal Ministry of Health

Mühlberger, Nikolai; Sroczynski, Gaby; Esteban, Eva; Mittendorf, Thomas; Miksad, Rebecca A.; Siebert, Uwe (Cambridge : Cambridge University Press, 2008)

Objectives: The aim of this study was to summarize the current evidence for the cost-effectiveness of primarily human papillomavirus (HPV) -based cervical cancer screening in settings with already established Papanicolaou ...

Now showing items 1-20 of 103

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