Forschungseinrichtungen: Recent submissions

  • A Chemical Chaperone Restores Connexin 26 Mutant Activity 
    Wang, Dahua; Wang, Hongling; Fan, Lu; Ludwig, Tobias; Wegner, Andre; Stahl, Frank; Harre, Jennifer; Warnecke, Athanasia; Zeilinger, Carsten (Washington, DC : ACS Publications, 2023)
    Mutations in connexin 26 (Cx26) cause hearing disorders of a varying degree. Herein, to identify compounds capable of restoring the function of mutated Cx26, a novel miniaturized microarray-based screening system was ...
  • Analysis of SARS-CoV-2 spike RBD binding to ACE2 and its inhibition by fungal cohaerin C using surface enhanced Raman spectroscopy 
    Wetzel, Christoph; Jansen-Olliges, Linda; Stadler, Marc; Surup, Frank; Zeilinger, Carsten; Roth, Bernhard (Washington, DC : Optica, 2023)
    The structure of the SARS-CoV-2 spike RBD and human ACE2 as well as changes in the structure due to binding activities were analysed using surface enhanced Raman spectroscopy. The inhibitor cohaerin C was applied to inhibit ...
  • Improvements to the detection and analysis of external surges in the North Sea 
    Böhme, Alexander; Gerkensmeier, Birgit; Bratz, Benedikt; Krautwald, Clemens; Müller, Olaf; Goseberg, Nils; Gönnert, Gabriele (Katlenburg-Lindau : European Geophysical Society, 2023)
    External surges are a key component of extreme water levels in the North Sea. Caused by low-pressure cells over the North Atlantic and amplified at the continental shelf, they can drive water-level changes of more than 1m ...
  • Theory of atom interferometry based on bragg diffraction and bloch oscillations 
    Fitzek, Florian (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2024)
    Atom interferometers are versatile quantum sensors that enable a wide range of high-precision and high-accuracy measurements ranging from fundamental physics to real-world applications. Large momentum transfer (LMT) ...
  • The subanalysis of Rheuma-VOR demonstrates a considerable need for rheumatological care 
    Hirsch, Stefanie; Hoeper, K.; Meyer-Olson, D.; Schwarting, A.; Gente, K.; Dreher, M.; Hoeper, J.; Witte, T.; Thiele, T. (Heidelberg : Springer, 2024)
    Background: Early diagnosis and treatment of inflammatory rheumatic diseases can prevent consequential damage such as permanently limited mobility and joint or organ damage. Simultaneously, there is an increasing deficit ...
  • Geführte Atominterferometrie im optischen Wellenleiterpotential 
    Bode, Sebastian (Hannover : Institutionelles Repositorium der Leibniz Universität, 2024)
    Quantensensoren auf Basis ultrakalter Gase bieten auf Grund ihrer Genauigkeit und Stabilität große Vorteile gegenüber klassischen Sensoren in der Inertialsensorik, fundamentalen Physik, Metrologie und Geodäsie. Die ...
  • Biofilm volume and acidification within initial biofilms formed in situ on buccally and palatally exposed bracket material 
    Loewe, Micha Frederic; Doll-Nikutta, Katharina; Stiesch, Meike; Schwestka-Polly, Rainer (München : Urban & Vogel, 2024)
    Purpose: Acidification by bacterial biofilms at the bracket/tooth interface is one of the most common problems in fixed orthodontic treatments, which can lead to white spot lesions (WSL) and caries. As lingual brackets ...
  • Activity-Based Protein Profiling Identifies Protein Disulfide-Isomerases as Target Proteins of the Volatile Salinilactones 
    Jerye, Karoline; Lüken, Helko; Steffen, Anika; Schlawis, Christian; Jänsch, Lothar; Schulz, Stefan; Brönstrup, Mark (Weinheim : Wiley-VCH, 2024)
    The salinilactones, volatile marine natural products secreted from Salinispora arenicola, feature a unique [3.1.0]-lactone ring system and cytotoxic activities through a hitherto unknown mechanism. To find their molecular ...
  • Investigation of the molecular switching process between spin crossover states of triazole complexes as basis for optical sensing applications 
    Günther, Axel; Deja, Yves; Kilic, Maximilian; Tran, Kevin; Kotra, Pavan; Renz, Franz; Kowalsky, Wolfgang; Roth, Bernhard ([London] : Macmillan Publishers Limited, part of Springer Nature, 2024)
    With the advent of the first laser sources and suitable detectors, optical sensor applications immediately also came into focus. During the last decades, a huge variety of optical sensor concepts were developed, yet the ...
  • Theoretical study of quantum gas experiments in an Earth-orbiting research laboratory 
    Pichery, Annie (Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2024-04)
    One of the major goals of fundamental physics is to unify general relativity, which describes macroscopic phenomena driven by the influence of gravity, with quantum mechanics, which focuses on effects at microscopic scales. ...
  • Learning analytics and the Universal Design for Learning (UDL): A clustering approach 
    Roski, Marvin; Sebastian, Ratan; Ewerth, Ralph; Hoppe, Anett; Nehring, Andreas (Amsterdam [u.a.] : Elsevier Science, 2024)
    In the context of inclusive education, Universal Design for Learning (UDL) is a framework used worldwide to create learning opportunities accessible to all learners. While much research focused on the design and students' ...
  • Investigation of chain-length selection by the tenellin iterative highly-reducing polyketide synthase 
    Schmidt, Katharina; Cox, Russell J. (London : RSC Publishing, 2024)
    The programming of widely distributed iterative fungal hr-PKS is mysterious, yet it is central for generating polyketide natural product diversity by controlling the chain length, β-processing level and methylation patterns ...
  • Exploring the fundamental limits of integrated beam splitters with arbitrary phase via topology optimization 
    Nanda, Abhishek; Kues, Michael; Calà Lesina, Antonio (Washington, DC : Soc., 2024)
    Optical beam splitters are essential for classical and quantum photonic on-chip systems. In integrated optical technology, a beam splitter can be implemented as a beam coupler with two input and two output ports. The output ...
  • QuoteKG: A Multilingual Knowledge Graph of Quotes 
    Kuculo, Tin; Gottschalk, Simon; Demidova, Elena (Cham, Switzerland : Springer, 2022)
    Quotes of public figures can mark turning points in history. A quote can explain its originator’s actions, foreshadowing political or personal decisions and revealing character traits. Impactful quotes cross language ...
  • Comparing Interface Layouts for the Presentation of Multimodal Search Results 
    Gritz, Wolfgang; Otto, Christian; Hoppe, Anett; Pardi, Georg; Kammerer, Yvonne; Ewerth, Ralph (New York, NY : Association for Computing Machinery, 2023)
    Today's search engines allow users to discover relevant information in different types of modalities or media, e.g., web pages, text documents, images, or videos. It is, however, a challenging task to present mixed-modality ...
  • Improving Generalization for Multimodal Fake News Detection 
    Tahmasebi, Sahar; Hakimov, Sherzod; Ewerth, Ralph; Müller-Budack, Eric (New York, NY : Association for Computing Machinery, 2023)
    The increasing proliferation of misinformation and its alarming impact have motivated both industry and academia to develop approaches for fake news detection. However, state-of-the-art approaches are usually trained on ...
  • Traditional Machine Learning Models and Bidirectional Encoder Representations From Transformer (BERT)-Based Automatic Classification of Tweets About Eating Disorders: Algorithm Development and Validation Study 
    Benítez-Andrades, José Alberto; Alija-Pérez, José-Manuel; Vidal, Maria-Esther; Pastor-Vargas, Rafael; García-Ordás, María Teresa (Toronto : [Verlag nicht ermittelbar], 2022)
    Background: Eating disorders affect an increasing number of people. Social networks provide information that can help. Objective: We aimed to find machine learning models capable of efficiently categorizing tweets about ...
  • Impact of electrically assisted bicycles on physical activity and traffic accident risk: A prospective observational study 
    Haufe, Sven; Boeck, Hedwig Theda; Häckl, Sebastian; Boyen, Johanna; Kück, Momme; van Rhee, Clara Catharina; Graf von der Schulenburg, Johann-Matthias; Zeidler, Jan; Schmidt, Torben; Johannsen, Heiko; Holzwart, Dennis; Koch, Armin; Tegtbur, Uwe (London : BMJ Publishing Group, 2022)
    Background Electrically assisted bicycles (e-bikes) have become increasingly popular and may facilitate active commuting and recreational cycling. Objective To evaluate the physical activity levels and usage characteristics ...
  • Understanding image-text relations and news values for multimodal news analysis 
    Cheema, Gullal S.; Hakimov, Sherzod; Müller-Budack, Eric; Otto, Christian; Bateman, John A.; Ewerth, Ralph (Lausanne : Frontiers Media, 2023)
    The analysis of news dissemination is of utmost importance since the credibility of information and the identification of disinformation and misinformation affect society as a whole. Given the large amounts of news data ...
  • "Outroduction”: A Research Agenda on Collegiality in University Settings 
    Cloete, Nico; Côté, Nancy; Crace, Logan; Delbridge, Rick; Denis, Jean-Louis; Drori, Gili S.; Eriksson-Zetterquist, Ulla; Gehman, Joel; Gerhardt, Lisa-Maria; Goldenstein, Jan; Harroche, Audrey; Jandrić, Jakov; Kosmützky, Anna; Krücken, Georg; Lee, Seungah S.; Lounsbury, Michael; Mizrahi-Shtelman, Ravit; Musselin, Christine; Gustafsson, Hampus Östh; Pineda, Pedro; Quattrone, Paolo; Ramirez, Francisco O.; Sahlin, Kerstin; van Schalkwyk, Francois; Walgenbach, Peter (Bingley : Emerald, 2023)
    Collegiality is the modus operandi of universities. Collegiality is central to academic freedom and scientific quality. In this way, collegiality also contributes to the good functioning of universities’ contribution to ...

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