Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus

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dc.identifier.uri http://dx.doi.org/10.15488/2422
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/2448
dc.contributor.author Neuser, Frauke
dc.contributor.author Zorn, Holger
dc.contributor.author Berger, Ralf Günter
dc.date.accessioned 2017-11-24T10:07:40Z
dc.date.available 2017-11-24T10:07:40Z
dc.date.issued 2000
dc.identifier.citation Neuser, F.; Zorn, H.; Berger, R.G.: Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus. In: Zeitschrift für Naturforschung - Section C Journal of Biosciences 55 (2000), Nr. 7-8, S. 560-568. DOI: https://doi.org/10.1515/znc-2000-7-814
dc.description.abstract The wild-type yeast strain Zygosaccharomyces bisporus CBS 702 produced a-hydroxy-ketones (acyloins) from amino acid precursors after transamination to the corresponding 2-oxo acids. The key enzyme of the subsequent decarboxylation and C-C bond forming reaction, pyruvate decarboxylase (PDC), was examined for its substrate- and stereo-specific-ity. A wide variety of saturated and unsaturated aliphatic and aromatic aldehydes was successfully converted to acyloins. 19 of the biotransformation products identified had not been reported as natural substances before. Product yields were strongly affected by substrate structure. © 2000, Verlag der Zeitschrift für Naturforschung. All rights reserved. eng
dc.language.iso eng
dc.publisher Berlin : De Gruyter
dc.relation.ispartofseries Zeitschrift für Naturforschung - Section C Journal of Biosciences 55 (2000), Nr. 7-8
dc.rights CC BY-NC-ND 3.0
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject Zygosaccharomyces bisporus eng
dc.subject Acyloin Formation eng
dc.subject Pyruvate Decarboxylase eng
dc.subject chemical bond eng
dc.subject decarboxylation eng
dc.subject enzyme specificity eng
dc.subject enzyme substrate eng
dc.subject genetic strain eng
dc.subject pyruvate decarboxylase eng
dc.subject stereospecificity eng
dc.subject wild relative eng
dc.subject yeast eng
dc.subject Zygosaccharomyces bisporus eng
dc.subject.ddc 570 | Biowissenschaften, Biologie ger
dc.title Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus
dc.type article
dc.type Text
dc.relation.essn 1865-7125
dc.relation.issn 0939-5075
dc.relation.doi https://doi.org/10.1515/znc-2000-7-814
dc.bibliographicCitation.issue 7-8
dc.bibliographicCitation.volume 55
dc.bibliographicCitation.firstPage 560
dc.bibliographicCitation.lastPage 568
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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