Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus

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Neuser, F.; Zorn, H.; Berger, R.G.: Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus. In: Zeitschrift für Naturforschung - Section C Journal of Biosciences 55 (2000), Nr. 7-8, S. 560-568. DOI: https://doi.org/10.1515/znc-2000-7-814

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To cite the version in the repository, please use this identifier: https://doi.org/10.15488/2422

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Abstract: 
The wild-type yeast strain Zygosaccharomyces bisporus CBS 702 produced a-hydroxy-ketones (acyloins) from amino acid precursors after transamination to the corresponding 2-oxo acids. The key enzyme of the subsequent decarboxylation and C-C bond forming reaction, pyruvate decarboxylase (PDC), was examined for its substrate- and stereo-specific-ity. A wide variety of saturated and unsaturated aliphatic and aromatic aldehydes was successfully converted to acyloins. 19 of the biotransformation products identified had not been reported as natural substances before. Product yields were strongly affected by substrate structure. © 2000, Verlag der Zeitschrift für Naturforschung. All rights reserved.
License of this version: CC BY-NC-ND 3.0
Document Type: article
Publishing status: publishedVersion
Issue Date: 2000
Appears in Collections:Naturwissenschaftliche Fakultät

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1 image of flag of Germany Germany 29 78.38%
2 image of flag of China China 6 16.22%
3 image of flag of Ukraine Ukraine 1 2.70%
4 image of flag of Japan Japan 1 2.70%

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