Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus

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Neuser, F.; Zorn, H.; Berger, R.G.: Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus. In: Zeitschrift für Naturforschung - Section C Journal of Biosciences 55 (2000), Nr. 7-8, S. 560-568. DOI:

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Sum total of downloads: 95

The wild-type yeast strain Zygosaccharomyces bisporus CBS 702 produced a-hydroxy-ketones (acyloins) from amino acid precursors after transamination to the corresponding 2-oxo acids. The key enzyme of the subsequent decarboxylation and C-C bond forming reaction, pyruvate decarboxylase (PDC), was examined for its substrate- and stereo-specific-ity. A wide variety of saturated and unsaturated aliphatic and aromatic aldehydes was successfully converted to acyloins. 19 of the biotransformation products identified had not been reported as natural substances before. Product yields were strongly affected by substrate structure. © 2000, Verlag der Zeitschrift für Naturforschung. All rights reserved.
License of this version: CC BY-NC-ND 3.0 Unported
Document Type: article
Publishing status: publishedVersion
Issue Date: 2000
Appears in Collections:Naturwissenschaftliche Fakultät

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1 image of flag of Germany Germany 76 80.00%
2 image of flag of China China 7 7.37%
3 image of flag of Japan Japan 4 4.21%
4 image of flag of United States United States 3 3.16%
5 image of flag of No geo information available No geo information available 1 1.05%
6 image of flag of Ukraine Ukraine 1 1.05%
7 image of flag of Romania Romania 1 1.05%
8 image of flag of Pakistan Pakistan 1 1.05%
9 image of flag of Anonymous Proxy Anonymous Proxy 1 1.05%

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