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dc.identifier.uri Walter, Johanna-Gabriela Heilkenbrinker, Alexandra Austerjost, Jonas Timur, Suna Stahl, Frank Scheper, Thomas 2017-11-24T07:40:29Z 2017-11-24T07:40:29Z 2012
dc.identifier.citation Walter, J.-G.; Heilkenbrinker, A.; Austerjost, J.; Timur, S.; Stahl, F. et al.: Aptasensors for small molecule detection. In: Zeitschrift für Naturforschung - Section B Journal of Chemical Sciences 67 (2012), Nr. 10, S. 976-986. DOI:
dc.description.abstract Aptamers are single-stranded oligonucleotides composed of RNA or DNA that are able to bind their corresponding targets via molecular recognition. Thus, aptamers can be thought of as nucleic acidbased alternatives to antibodies and have attracted attention as receptors in biosensors. Aptamers seem to be ideal biological recognition elements, since they enable the design of intelligent sensors based on their specific properties. Especially the fact that most aptamers undergo conformational changes during the binding of the target and their oligonucleotide nature can be used to rationally design novel sensing strategies. This review focuses on aptasensors for the detection of small molecules. In the first part, aptamers, their generation and their properties are briefly described. In the second part, different design strategies for aptasensors are reviewed, and examples for the detection of small molecules are given. © 2012 Verlag der Zeitschrift fur Naturforschung. eng
dc.language.iso eng
dc.publisher Berlin : De Gruyter
dc.relation.ispartofseries Zeitschrift für Naturforschung - Section B Journal of Chemical Sciences 67 (2012), Nr. 10
dc.rights CC BY-NC-ND 3.0 Unported
dc.subject Aptamer eng
dc.subject Aptasensor eng
dc.subject Biosensor eng
dc.subject Small molecule eng
dc.subject.ddc 540 | Chemie ger
dc.title Aptasensors for small molecule detection eng
dc.type article
dc.type Text
dc.relation.essn 1865-7117
dc.relation.issn 0932-0776
dc.bibliographicCitation.issue 10
dc.bibliographicCitation.volume 67
dc.bibliographicCitation.firstPage 976
dc.bibliographicCitation.lastPage 986
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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