Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL

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dc.identifier.uri http://dx.doi.org/10.15488/1611
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/1636
dc.contributor.author Matena, Julia
dc.contributor.author Petersen, Svea
dc.contributor.author Gieseke, Matthias
dc.contributor.author Teske, Michael
dc.contributor.author Beyerbach, Martin
dc.contributor.author Kampmann, Andreas
dc.contributor.author Escobar, Hugo Murua
dc.contributor.author Gellrich, Nils-Claudius
dc.contributor.author Haferkamp, Heinz
dc.contributor.author Nolte, Ingo
dc.date.accessioned 2017-06-14T12:34:50Z
dc.date.available 2017-06-14T12:34:50Z
dc.date.issued 2015
dc.identifier.citation Matena, Julia; Petersen, Svea; Gieseke, Matthias; Teske, Michael; Beyerbach, Martin et al.: Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL. In: International Journal of Molecular Sciences 16 (2015), Nr. 6, S. 13287-13301. DOI: https://doi.org/10.3390/ijms160613287
dc.description.abstract Degradable implant material for bone remodeling that corresponds to the physiological stability of bone has still not been developed. Promising degradable materials with good mechanical properties are magnesium and magnesium alloys. However, excessive gas production due to corrosion can lower the biocompatibility. In the present study we used the polymer coating polycaprolactone (PCL), intended to lower the corrosion rate of magnesium. Additionally, improvement of implant geometry can increase bone remodeling. Porous structures are known to support vessel ingrowth and thus increase osseointegration. With the selective laser melting (SLM) process, defined open porous structures can be created. Recently, highly reactive magnesium has also been processed by SLM. We performed studies with a flat magnesium layer and with porous magnesium implants coated with polymers. The SLM produced magnesium was compared with the titanium alloy TiAl6V4, as titanium is already established for the SLM-process. For testing the biocompatibility, we used primary murine osteoblasts. Results showed a reduced corrosion rate and good biocompatibility of the SLM produced magnesium with PCL coating. eng
dc.description.sponsorship DFG/299/11-1
dc.language.iso eng
dc.publisher Basel : MDPI AG
dc.relation.ispartofseries International Journal of Molecular Sciences 16 (2015), Nr. 6
dc.rights CC BY 4.0
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject in-vitro eng
dc.subject donor site eng
dc.subject mg alloys eng
dc.subject bone regeneration eng
dc.subject scaffolds eng
dc.subject biocompatibility eng
dc.subject biodegradation eng
dc.subject corrosion eng
dc.subject neovascularization eng
dc.subject degradation eng
dc.subject.ddc 540 | Chemie ger
dc.subject.ddc 570 | Biowissenschaften, Biologie ger
dc.title Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL
dc.type article
dc.type Text
dc.relation.issn 1422-0067
dc.relation.doi https://doi.org/10.3390/ijms160613287
dc.bibliographicCitation.issue 6
dc.bibliographicCitation.volume 16
dc.bibliographicCitation.firstPage 13287
dc.bibliographicCitation.lastPage 13301
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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