Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL

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Matena, Julia; Petersen, Svea; Gieseke, Matthias; Teske, Michael; Beyerbach, Martin et al.: Comparison of Selective Laser Melted Titanium and Magnesium Implants Coated with PCL. In: International Journal of Molecular Sciences 16 (2015), Nr. 6, S. 13287-13301. DOI: https://doi.org/10.3390/ijms160613287

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Sum total of downloads: 119




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Abstract: 
Degradable implant material for bone remodeling that corresponds to the physiological stability of bone has still not been developed. Promising degradable materials with good mechanical properties are magnesium and magnesium alloys. However, excessive gas production due to corrosion can lower the biocompatibility. In the present study we used the polymer coating polycaprolactone (PCL), intended to lower the corrosion rate of magnesium. Additionally, improvement of implant geometry can increase bone remodeling. Porous structures are known to support vessel ingrowth and thus increase osseointegration. With the selective laser melting (SLM) process, defined open porous structures can be created. Recently, highly reactive magnesium has also been processed by SLM. We performed studies with a flat magnesium layer and with porous magnesium implants coated with polymers. The SLM produced magnesium was compared with the titanium alloy TiAl6V4, as titanium is already established for the SLM-process. For testing the biocompatibility, we used primary murine osteoblasts. Results showed a reduced corrosion rate and good biocompatibility of the SLM produced magnesium with PCL coating.
License of this version: CC BY 4.0
Document Type: article
Publishing status: publishedVersion
Issue Date: 2015
Appears in Collections:Fakultät für Maschinenbau

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pos. country downloads
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1 image of flag of Germany Germany 102 85.71%
2 image of flag of China China 5 4.20%
3 image of flag of Czech Republic Czech Republic 4 3.36%
4 image of flag of United States United States 3 2.52%
5 image of flag of No geo information available No geo information available 2 1.68%
6 image of flag of Australia Australia 2 1.68%
7 image of flag of United Arab Emirates United Arab Emirates 1 0.84%

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