Aptamer Microarrays-Current Status and Future Prospects

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dc.identifier.uri http://dx.doi.org/10.15488/1556
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/1581
dc.contributor.author Witt, Martin
dc.contributor.author Walter, Johanna-Gabriela
dc.contributor.author Stahl, Frank
dc.date.accessioned 2017-05-30T12:17:52Z
dc.date.available 2017-05-30T12:17:52Z
dc.date.issued 2015
dc.identifier.citation Witt, Martin; Walter, Johanna-Gabriela; Stahl, Frank: Aptamer Microarrays-Current Status and Future Prospects. In: Microarrays 4 (2015), Nr. 2, S. 115-132. DOI: https://doi.org/10.3390/microarrays4020115
dc.description.abstract Microarray technologies are state of the art in biological research, which requires fast genome, proteome and transcriptome analysis technologies. Often antibodies are applied in protein microarrays as proteomic tools. Since the generation of antibodies against toxic targets or small molecules including organic compounds remains challenging the use of antibodies may be limited in this context. In contrast to this, aptamer microarrays provide alternative techniques to circumvent these limitations. In this article we review the latest developments in aptamer microarray technology. We discuss similarities and differences between DNA and aptamer microarrays and shed light on the post synthesis immobilization of aptamers including corresponding effects on the microarray performance. Finally, we highlight current limitations and future prospects of aptamer microarray technology. eng
dc.language.iso eng
dc.publisher Basel : MDPI AG
dc.relation.ispartofseries Microarrays 4 (2015), Nr. 2
dc.rights CC BY 4.0 Unported
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject aptamer eng
dc.subject microarray eng
dc.subject multiplex eng
dc.subject protein detection eng
dc.subject small molecules eng
dc.subject.ddc 570 | Biowissenschaften, Biologie ger
dc.title Aptamer Microarrays-Current Status and Future Prospects eng
dc.type article
dc.type Text
dc.relation.issn 2076-3905
dc.relation.doi https://doi.org/10.3390/microarrays4020115
dc.bibliographicCitation.issue 2
dc.bibliographicCitation.volume 4
dc.bibliographicCitation.firstPage 115
dc.bibliographicCitation.lastPage 132
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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