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Original version
Jütte, L.; Sharma, G.; Patel, H.; Roth, B.: Registration of polarimetric images for in vivo skin diagnostics. In: Journal of Biomedical Optics 27 (2022), Nr. 09, 96001. DOI: https://doi.org/10.1117/1.jbo.27.9.096001
SIGNIFICANCE: Mueller matrix (MM) polarimetry is a promising tool for the detection of skin cancer. Polarimetric in vivo measurements often suffer from misalignment of the polarimetric images due to motion, which can lead to false results. AIM: We aim to provide an easy-to-implement polarimetric image data registration method to ensure proper image alignment. APPROACH: A feature-based image registration is implemented for an MM polarimeter for phantom and in vivo human skin measurements. RESULTS: We show that the keypoint-based registration of polarimetric images is necessary for in vivo skin polarimetry to ensure reliable results. Further, we deliver an efficient semiautomated method for the registration of polarimetric images. CONCLUSIONS: Image registration for in vivo polarimetry of human skin is required for improved diagnostics and can be efficiently enhanced with a keypoint-based approach.