Pilot-Scale Production of the Natural Colorant Laetiporic Acid, Its Stability and Potential Applications

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dc.identifier.uri https://www.repo.uni-hannover.de/handle/123456789/13500
dc.identifier.uri https://doi.org/10.15488/13391
dc.contributor.author Bergmann, Pia
dc.contributor.author Frank, Christina
dc.contributor.author Reinhardt, Olena
dc.contributor.author Takenberg, Meike
dc.contributor.author Werner, Anett
dc.contributor.author Berger, Ralf G.
dc.contributor.author Ersoy, Franziska
dc.contributor.author Zschaetzsch, Marlen
dc.date.accessioned 2023-03-24T09:18:58Z
dc.date.available 2023-03-24T09:18:58Z
dc.date.issued 2022
dc.identifier.citation Bergmann, P.; Frank, C.; Reinhardt, O.; Takenberg, M.; Werner, A. et al.: Pilot-Scale Production of the Natural Colorant Laetiporic Acid, Its Stability and Potential Applications. In: Fermentation 8 (2022), Nr. 12, 684. DOI: https://doi.org/10.3390/fermentation8120684
dc.description.abstract Laetiporus sulphureus, a wood-decaying basidiomycete, produces yellow-orange pigments in fruiting bodies and, as was recently shown, in submerged cultivated mycelia. Out of four strains, the most potent laetiporic acid producer was identified and its yield compared in different media. The complex Moser b medium was replaced by potato dextrose broth, achieving higher yields at a lower cost. Cultivation was then scaled up from shake flask to a 7 L stirred tank bioreactor. Optimization of parameters led to increased product concentrations up to 1 g L−1, the highest yield reported so far. An in situ product recovery strategy with a biphasic system was established, increasing the yield by 19% on the shake flask scale. A crude ethanolic extract of the biomass was examined for color stability and application trials. In contrast to what has been suggested in the past, the pigment showed limited long-term stability to oxygen and light, but was stable under storage in the dark at 4 °C under nitrogen. The orange extract was successfully incorporated into different matrices like foods, cosmetics and textiles. Laetiporic acid can potentially replace petrochemical based synthetic dyes, and can thus support the development of a circular bioeconomy. eng
dc.language.iso eng
dc.publisher Basel : MDPI
dc.relation.ispartofseries Fermentation 8 (2022), Nr. 12
dc.rights CC BY 4.0 Unported
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject laetiporic acid eng
dc.subject Laetiporus sulphureus eng
dc.subject natural colorants eng
dc.subject natural dye eng
dc.subject basidiomycete eng
dc.subject bioprocess eng
dc.subject submerged fermentation eng
dc.subject biotechnology eng
dc.subject.ddc 570 | Biowissenschaften, Biologie ger
dc.title Pilot-Scale Production of the Natural Colorant Laetiporic Acid, Its Stability and Potential Applications
dc.type Article
dc.type Text
dc.relation.essn 2311-5637
dc.relation.doi https://doi.org/10.3390/fermentation8120684
dc.bibliographicCitation.issue 12
dc.bibliographicCitation.volume 8
dc.bibliographicCitation.firstPage 684
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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