Zusammenfassung: | |
Background/Aim: Evaluation of cardiovascular risk profile in 154 German vegans. Methods: Cross-sectional study, Germany. Study instruments: 2 FFQ, 2 questionnaires, analyses of fasting venous blood samples. Results: The total study population had a low BMI (mean: 22.3 kg/m2), a moderate blood pressure (mean: 120/75 mm Hg), an extremely low consumption of alcohol (mean: 0.77 g/day) and 96.8% were nonsmokers. Moderate physical activity (PAL) was reported by nearly 50%, whereas 22.7% declared to have a high PAL (>3 h/week). Median triacylglycerol (TG) was 0.81 mmol/l, total cholesterol (TC) was 4.33 mmol/l, HDL was 1.34 mmol/l. The mean TC/HDL-ratio was 3.3. Lipoprotein(a) (Lp(a)) was 8.13 mg/dl, concentrations of >30 mg/dl were prevalent in 25% of the participants. In general, status of folate and pyridoxine were sufficient, while 49.7% showed cobalamin concentrations <150 pmol/l. Plasma homocysteine levels were slightly elevated (median: 12.5 µmol/l). Cobalamin concentration and duration of vegan nutrition were the main determinants of homocysteine in the total study population. Conclusion: Although TC and LDL concentrations were favorable, low HDL and elevated homocysteine and Lp(a) concentrations were unfavorable. Overall, these results confirm the notion that a vegan diet is deficient in vitamin B12, which may have an unfavorable effect on CHD risk.
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Lizenzbestimmungen: | Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. |
Publikationstyp: | Article |
Publikationsstatus: | publishedVersion |
Erstveröffentlichung: | 2005 |
Schlagwörter (englisch): | Cardiovascular risk, Cholesterol, Homocysteine, Lipoprotein(a), Vegan, alcohol, cholesterol, cobalamin, folic acid, high density lipoprotein, homocysteine, lipoprotein A, low density lipoprotein, pyridoxine, triacylglycerol, adult, alcohol consumption, article, blood pressure, blood sampling, body mass, cardiovascular risk, cardiovascular system, cholesterol blood level, controlled study, diet, diet restriction, female, Germany, human, lifestyle, lipoprotein blood level, major clinical study, male, physical activity, population research, priority journal, questionnaire, risk assessment, triacylglycerol blood level, vegetarian diet, venous blood, vitamin blood level, Adult, Alcohol Drinking, Cardiovascular Diseases, Cross-Sectional Studies, Diet, Vegetarian, Energy Intake, Exercise, Female, Germany, Humans, Life Style, Lipids, Male, Middle Aged, Nutritional Requirements, Questionnaires, Risk Factors, Smoking, Vitamin B 12, Vitamin B 12 Deficiency |
Fachliche Zuordnung (DDC): | 610 | Medizin, Gesundheit |
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