Reactive multilayer systems (RMS) represent an innovative heat source for the establishment of solder joints. They offer fast bonding processes that introduce very little thermal input and internal stress on the bonded parts. The current application process of RMS is predominantly manual labor. There are a couple of challenges to be overcome to automate this process, a requirement for its introduction into industrial production. In this paper we evaluate the requirements for an automated joining process with RMS and devise a concept of a modular assembly system for different product structures. Furthermore we show our results in gently and reliably gripping and handling of RMS.