dc.identifier.uri |
http://dx.doi.org/10.15488/10918 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/11000 |
|
dc.contributor.author |
Siller, Ina G.
|
|
dc.contributor.author |
Preuss, John-Alexander
|
|
dc.contributor.author |
Urmann, Katharina
|
|
dc.contributor.author |
Hoffmann, Michael R.
|
|
dc.contributor.author |
Scheper, Thomas
|
|
dc.contributor.author |
Bahnemann, Janina
|
|
dc.date.accessioned |
2021-05-14T06:27:49Z |
|
dc.date.available |
2021-05-14T06:27:49Z |
|
dc.date.issued |
2020 |
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dc.identifier.citation |
Siller, I.G.; Preuss, J.-A.; Urmann, K.; Hoffmann, M.R.; Scheper, T. et al.: 3D-Printed Flow Cells for Aptamer-Based Impedimetric Detection of E. coli Crooks Strain . In: Sensors 20 (2020), Nr. 16, 4421. DOI: https://doi.org/10.3390/s20164421 |
|
dc.description.abstract |
Electrochemical spectroscopy enables rapid, sensitive, and label-free analyte detection without the need of extensive and laborious labeling procedures and sample preparation. In addition, with the emergence of commercially available screen-printed electrodes (SPEs), a valuable, disposable alternative to costly bulk electrodes for electrochemical (bio-)sensor applications was established in recent years. However, applications with bare SPEs are limited and many applications demand additional/supporting structures or flow cells. Here, high-resolution 3D printing technology presents an ideal tool for the rapid and flexible fabrication of tailor-made, experiment-specific systems. In this work, flow cells for SPE-based electrochemical (bio-)sensor applications were designed and 3D printed. The successful implementation was demonstrated in an aptamer-based impedimetric biosensor approach for the detection of Escherichia coli (E. coli) Crooks strain as a proof of concept. Moreover, further developments towards a 3D-printed microfluidic flow cell with an integrated micromixer also illustrate the great potential of high-resolution 3D printing technology to enable homogeneous mixing of reagents or sample solutions in (bio-)sensor applications. |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Basel : MDPI |
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dc.relation.ispartofseries |
Sensors 20 (2020), Nr. 16 |
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dc.rights |
CC BY 4.0 Unported |
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dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
additive manufacturing |
eng |
dc.subject |
impedimetric biosensor |
eng |
dc.subject |
aptasensor |
eng |
dc.subject |
screen-printed electrodes |
eng |
dc.subject.ddc |
620 | Ingenieurwissenschaften und Maschinenbau
|
ger |
dc.title |
3D-Printed Flow Cells for Aptamer-Based Impedimetric Detection of E. coli Crooks Strain |
|
dc.type |
Article |
|
dc.type |
Text |
|
dc.relation.essn |
1424-8220 |
|
dc.relation.doi |
https://doi.org/10.3390/s20164421 |
|
dc.bibliographicCitation.issue |
16 |
|
dc.bibliographicCitation.volume |
20 |
|
dc.bibliographicCitation.firstPage |
4421 |
|
dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
|