dc.identifier.uri |
http://dx.doi.org/10.15488/9356 |
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dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/9410 |
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dc.contributor.author |
Hantke, Verena
|
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dc.contributor.author |
Wang, Chongqing
|
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dc.contributor.author |
Skellam, Elizabeth J.
|
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dc.contributor.author |
Cox, Russell J.
|
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dc.date.accessioned |
2020-02-14T11:22:59Z |
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dc.date.available |
2020-02-14T11:22:59Z |
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dc.date.issued |
2019 |
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dc.identifier.citation |
Hantke, V.; Wang, C.; Skellam, E.J.; Cox, R.J.: Function of pathway specific regulators in the ACE1 and pyrichalasin H biosynthetic gene clusters. In: RSC Advances 61 (2019), 35797. DOI: https://doi.org/10.1039/c9ra07028a |
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dc.description.abstract |
Ectopic expression of BC1 which encodes a putative pathway specific transcription factor from the ACE1 biosynthetic gene cluster of the rice pathogen Pyricularia oryzae Guy11 did not lead to the production of ACE1-related compounds. However the known compound hinnulin A was formed. A putative partial gene cluster potentially involved in the biosynthesis of hinnulin A and DHN melanin was validated by RT-PCR and a possible biosynthetic pathway is proposed. Ectopic expression of pyiR which encodes a pathway specific transcription factor from the pyrichalasin H biosynthetic gene cluster in Magnaporthe grisea NI980 led to the apparent up-regulation of the pyi cluster and a 3-fold increase in pyrichalasin production under standard fermentation conditions, but did not lead to the formation of new compounds. |
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dc.language.iso |
eng |
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dc.publisher |
London : RSC |
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dc.relation.ispartofseries |
RSC Advances 61 (2019) |
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dc.rights |
CC BY-NC 3.0 Unported |
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dc.rights.uri |
https://creativecommons.org/licenses/by-nc/3.0/ |
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dc.subject |
ACE1 |
eng |
dc.subject |
Pyricularia oryzae |
eng |
dc.subject |
compounds |
eng |
dc.subject.ddc |
540 | Chemie
|
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dc.title |
Function of pathway specific regulators in the ACE1 and pyrichalasin H biosynthetic gene clusters |
eng |
dc.type |
Article |
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dc.type |
Text |
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dc.relation.doi |
10.1039/c9ra07028a |
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dc.bibliographicCitation.firstPage |
35797 |
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dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
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