• Varying the sustained release of BMP-2 from chitosan nanogel-functionalized polycaprolactone fiber mats by different polycaprolactone surface modifications 

  Sundermann, Julius; Oehmichen, Sarah; Sydow, Steffen; Burmeister, Laura; Quaas, Bastian; Hänsch, Robert; Rinas, Ursula; Hoffmann, Andrea; Menzel, Henning; Bunjes, Heike (New York, NY [u.a.] : Wiley, 2021)

  Polycaprolactone (PCL) fiber mats with different surface modifications were functionalized with a chitosan nanogel coating to attach the growth factor human bone morphogenetic protein 2 (BMP-2). Three different hydrophilic ...
• Facile Synthesis of a Croconaine-Based Nanoformulation for Optoacoustic Imaging and Photothermal Therapy 

  Liu, Nian; O'Connor, Patrick; Gujrati, Vipul; Gorpas, Dimitris; Glasl, Sarah; Blutke, Andreas; Walch, Axel; Kleigrewe, Karin; Sattler, Michael; Plettenburg, Oliver; Ntziachristos, Vasilis (Weinheim : Wiley-VCH, 2021)

  Near-infrared (NIR) light absorbing theranostic agents can integrate optoacoustic imaging and photothermal therapy for effective personalized precision medicine. However, most of these agents face the challenges of unstable ...
• Contrasting pathways of carbon sequestration in paddy and upland soils 

  Chen, Xiangbi; Hu, Yajun; Xia, Yinhang; Zheng, Shengmeng; Ma, Chong; Rui, Yichao; He, Hongbo; Huang, Daoyou; Zhang, Zhenhua; Ge, Tida; Wu, Jinshui; Guggenberger, Georg; Kuzyakov, Yakov; Su, Yirong (Oxford [u.a.] : Wiley-Blackwell, 2021)

  Paddy soils make up the largest anthropogenic wetlands on earth, and are characterized by a prominent potential for organic carbon (C) sequestration. By quantifying the plant- and microbial-derived C in soils across four ...
• Methanotrophs: Discoveries, Environmental Relevance, and a Perspective on Current and Future Applications 

  Guerrero-Cruz, Simon; Vaksmaa, Annika; Horn, Marcus A.; Niemann, Helge; Pijuan, Maite; Ho, Adrian (Lausanne : Frontiers Media, 2021)

  Methane is the final product of the anaerobic decomposition of organic matter. The conversion of organic matter to methane (methanogenesis) as a mechanism for energy conservation is exclusively attributed to the archaeal ...
• Recruitment of phospholipase Cγ1 to the nonstructural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation 

  Samarina, Naira; Ssebyatika, George; Tikla, Tanvi; Waldmann, Ja-Yun; Abere, Bizunesh; Nanna, Vittoria; Marasco, Michelangelo; Carlomagno, Teresa; Krey, Thomas; Schulz, Thomas F. (Lawrence, Kan. : PLoS, 2021)

  Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of multicentric Castleman’s Disease (MCD), as well as an ...
• Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications 

  Altincekic, Nadide; Korn, Sophie Marianne; Qureshi, Nusrat Shahin; Dujardin, Marie; Ninot-Pedrosa, Martí; Abele, Rupert; Abi Saad, Marie Jose; Alfano, Caterina; Almeida, Fabio C. L.; Alshamleh, Islam; de Amorim, Gisele Cardoso; Anderson, Thomas K.; Anobom, Cristiane D.; Anorma, Chelsea; Bains, Jasleen Kaur; Bax, Adriaan; Blackledge, Martin; Blechar, Julius; Böckmann, Anja; Brigandat, Louis; Bula, Anna; Bütikofer, Matthias; Camacho-Zarco, Aldo R.; Carlomagno, Teresa; Caruso, Icaro Putinhon; Ceylan, Betül; Chaikuad, Apirat; Chu, Feixia; Cole, Laura; Crosby, Marquise G.; de Jesus, Vanessa; Dhamotharan, Karthikeyan; Felli, Isabella C.; Ferner, Jan; Fleischmann, Yanick; Fogeron, Marie-Laure; Fourkiotis, Nikolaos K.; Fuks, Christin; Fürtig, Boris; Gallo, Angelo; Gande, Santosh L.; Gerez, Juan Atilio; Ghosh, Dhiman; Gomes-Neto, Francisco; Gorbatyuk, Oksana; Guseva, Serafima; Hacker, Carolin; Häfner, Sabine; Hao, Bing; Hargittay, Bruno; Henzler-Wildman, K.; Hoch, Jeffrey C.; Hohmann, Katharina F.; Hutchison, Marie T.; Jaudzems, Kristaps; Jović, Katarina; Kaderli, Janina; Kalniņš, Gints; Kaņepe, Iveta; Kirchdoerfer, Robert N.; Kirkpatrick, John; Knapp, Stefan; Krishnathas, Robin; Kutz, Felicitas; zur Lage, Susanne; Lambertz, Roderick; Lang, Andras; Laurents, Douglas; Lecoq, Lauriane; Linhard, Verena; Löhr, Frank; Malki, Anas; Bessa, Luiza Mamigonian; Martin, Rachel W.; Matzel, Tobias; Maurin, Damien; McNutt, Seth W.; Mebus-Antunes, Nathane Cunha; Meier, Beat H.; Meiser, Nathalie; Mompeán, Miguel; Monaca, Elisa; Montserret, Roland; Mariño Perez, Laura; Moser, Celine; Muhle-Goll, Claudia; Neves-Martins, Thais Cristtina; Ni, Xiamonin; Norton-Baker, Brenna; Pierattelli, Roberta; Pontoriero, Letizia; Pustovalova, Yulia; Ohlenschläger, Oliver; Orts, Julien; Da Poian, Andrea T.; Pyper, Dennis J.; Richter, Christian; Riek, Roland; Rienstra, Chad M.; Robertson, Angus; Pinheiro, Anderson S.; Sabbatella, Raffaele; Salvi, Nicola; Saxena, Krishna; Schulte, Linda; Schiavina, Marco; Schwalbe, Harald; Silber, Mara; Almeida, Marcius da Silva; Sprague-Piercy, Marc A.; Spyroulias, Georgios A.; Sreeramulu, Sridhar; Tants, Jan-Niklas; Tārs, Kaspars; Torres, Felix; Töws, Sabrina; Treviño, Miguel Á.; Trucks, Sven; Tsika, Aikaterini C.; Varga, Krisztina; Wang, Ying; Weber, Marco E.; Weigand, Julia E.; Wiedemann, Christoph; Wirmer-Bartoschek, Julia; Wirtz Martin, Maria Alexandra; Zehnder, Johannes; Hengesbach, Martin; Schlundt, Andreas (Lausanne : Frontiers, 2021)

  The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses a severe threat to humanity and demands the redirection of scientific efforts and criteria to organized research projects. The international ...
• Exceeding the threshold value for Trioza apicalis Förster 1848 in carrot fields did not cause damage as revealed during monitoring in Germany from 2017–2020 

  Sauer, J.; Dewert, A.; Hondelmann, P.; Meyhöfer, R.; Hommes, M.; Buck, H.; Ulrichs, C.; Vogler, U. (Berlin ; Heidelberg : Springer, 2021)

  The carrot psyllid Trioza apicalis Förster 1848 is a carrot pest in Europe that can cause serious damages in case of massive occurrence. Damages up to a total loss of yield have been reported from Scandinavian countries ...
• Strategies for RNA Resonance Assignment by 13C/15N- and 1H-Detected Solid-State NMR Spectroscopy 

  Aguion, Philipp Innig; Marchanka, Alexander (Lausanne : Frontiers, 2021)

  Magic angle spinning (MAS) solid-state NMR (ssNMR) is an established tool that can be applied to non-soluble or non-crystalline biomolecules of any size or complexity. The ssNMR method advances rapidly due to technical ...
• Bridging Microbial Functional Traits With Localized Process Rates at Soil Interfaces 

  Blagodatskaya, Evgenia; Tarkka, Mika; Knief, Claudia; Koller, Robert; Peth, Stephan; Schmidt, Volker; Spielvogel, Sandra; Uteau, Daniel; Weber, Matthias; Razavi, Bahar S. (Lausanne : Frontiers Media, 2021)

  In this review, we introduce microbially-mediated soil processes, players, their functional traits, and their links to processes at biogeochemical interfaces [e.g., rhizosphere, detritusphere, (bio)-pores, and aggregate ...
• Editorial: Exploring and Engineering Plant Specialized Metabolism: Latest Advances and New Horizons 

  Franke, Jakob; Zhang, Yang; Dang, Thu-Thuy T. (Lausanne : Frontiers Media, 2021)

  [no abstract available]
• Self-Assembled Nanoparticles Based on Block-Copolymers of Poly(2-Deoxy-2-methacrylamido-d-glucose)/Poly(N-Vinyl Succinamic Acid) with Poly(O-Cholesteryl Methacrylate) for Delivery of Hydrophobic Drugs 

  Levit, Mariia; Vdovchenko, Alena; Dzhuzha, Apollinariia; Zashikhina, Natalia; Katernyuk, Elena; Gostev, Alexey; Sivtsov, Eugene; Lavrentieva, Antonina; Tennikova, Tatiana; Korzhikova-Vlakh, Evgenia (Basel : Molecular Diversity Preservation International, 2021)

  The self-assembly of amphiphilic block-copolymers is a convenient way to obtain soft nanomaterials of different morphology and scale. In turn, the use of a biomimetic approach makes it possible to synthesize polymers with ...
• Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung 

  Lüdtke, Timo H.; Wojahn, Irina; Kleppa, Marc-Jens; Schierstaedt, Jasper; Christoffels, Vincent M.; Künzler, Patrick; Kispert, Andreas (London : BioMed Central, 2021)

  Background: Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial ...
• Paving the Way to Overcome Antifungal Drug Resistance: Current Practices and Novel Developments for Rapid and Reliable Antifungal Susceptibility Testing 

  Heuer, Christopher; Bahnemann, Janina; Scheper, Thomas; Segal, Ester (Weinheim : WILEY-VCH Verlag GmbH & Co. KGaA, 2021)

  The past year has established the link between the COVID-19 pandemic and the global spread of severe fungal infections; thus, underscoring the critical need for rapid and realizable fungal disease diagnostics. While in ...
• Earth Observation Data-Driven Cropland Soil Monitoring: A Review 

  Tziolas, Nikolaos; Tsakiridis, Nikolaos; Chabrillat, Sabine; Demattê, José A. M.; Ben-Dor, Eyal; Gholizadeh, Asa; Zalidis, George; van Wesemael, Bas (Basel : MDPI, 2021)

  We conducted a systematic review and inventory of recent research achievements related to spaceborne and aerial Earth Observation (EO) data-driven monitoring in support of soil-related strategic goals for a three-year ...
• Piper crocatum Ruiz & Pav. ameliorates wound healing through p53, E-cadherin and SOD1 pathways on wounded hyperglycemia fibroblasts 

  Setyawati, Andina; Wahyuningsih, Mae Sri Hartati; Nugrahaningsih, Dwi Aris Agung; Effendy, Christantie; Fneish, Firas; Fortwengel, Gerhard (Amsterdam [u.a.] : Elsevier, 2021)

  Introduction: Piper crocatum Ruiz & Pav (P. crocatum) has been reported to accelerate the diabetic wound healing process empirically. Some studies showed the benefits of P. crocatum in treating various diseases but its ...
• Fused Deposition Modeling of Microfluidic Chips in Transparent Polystyrene 

  Mader, Markus; Rein, Christof; Konrat, Eveline; Meermeyer, Sophia Lena; Lee-Thedieck, Cornelia; Kotz-Helmer, Frederik; Rapp, Bastian E. (Basel : MDPI, 2021)

  Polystyrene (PS) is one of the most commonly used thermoplastic materials worldwide and plays a ubiquitous role in today’s biomedical and life science industry and research. The main advantage of PS lies in its facile ...
• Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics 

  Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Wögrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Frieß, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Königshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Önder; Burgstaller, Gerald (Washington, DC [u.a.] : Assoc., 2021)

  Fibrogenic processes instigate fatal chronic diseases leading to organ failure and death. Underlying biological processes involve induced massive deposition of extracellular matrix (ECM) by aberrant fibroblasts. We subjected ...
• Temperature-Sensitive Localized Surface Plasmon Resonance of α-NiS Nanoparticles 

  Himstedt, Rasmus; Baabe, Dirk; Wesemann, Christoph; Bessel, Patrick; Hinrichs, Dominik; Schlosser, Anja; Bigall, Nadja C.; Dorfs, Dirk (Washington, DC : Soc., 2021)

  The presented work shows a synthesis route to obtain nanoparticles of the hexagonal α-NiS phase and core-shell particles where the same material is grown onto previously prepared Au seeds. In the bulk, this nickel sulfide ...
• Surface moisture increases microcracking and water vapour permeance of apple fruit skin 

  Khanal, B.P.; Imoro, Y.; Chen, Y.H.; Straube, J.; Knoche, M. (Oxford [u.a.] : Wiley- Blackwell, 2020)

  Surface moisture induces microcracking in the cuticle of fruit skins. Our objective was to study the effects of surface moisture on cuticular microcracking, the permeance to water vapour and russeting in developing ‘Pinova’ ...
• Noble-Metal Nanorod Cryoaerogels with Electrocatalytically Active Surface Sites 

  Zámbó, Dániel; Rusch, Pascal; Lübkemann, Franziska; Bigall, Nadja C. (Washington, DC : Soc., 2021)

  Noble-metal-based electrocatalysts usually contain small nanoparticle building blocks to ensure a high specific surface area as the scene for the surface processes. Here, we show that relatively large noble-metal nanorods ...

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