Promoting beneficial and inhibiting undesirable biofilm formation with mangrove extracts

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dc.identifier.uri Glasenapp, Yvana Catto, Cristina Villa, Federica Saracchi, Marco Cappitelli, Francesca Papenbrock, Jutta 2019-12-11T16:44:50Z 2019-12-11T16:44:50Z 2019
dc.identifier.citation Glasenapp, Y.; Catto, C.; Villa, F.; Saracchi, M.; Cappitelli, F.; Papenbrock, J.: Promoting beneficial and inhibiting undesirable biofilm formation with mangrove extracts. In: International Journal of Molecular Sciences 20 (2019), Nr. 14, 3549. DOI:
dc.description.abstract The extracts of two mangrove species, Bruguiera cylindrica and Laguncularia racemosa, have been analyzed at sub-lethal concentrations for their potential to modulate biofilm cycles (i.e., adhesion, maturation, and detachment) on a bacterium, yeast, and filamentous fungus. Methanolic leaf extracts were also characterized, and MS/MS analysis has been used to identify the major compounds. In this study, we showed the following. (i) Adhesion was reduced up to 85.4% in all the models except for E. coli, where adhesion was promoted up to 5.10-fold. (ii) Both the sum and ratio of extracellular polysaccharides and proteins in mature biofilm were increased up to 2.5-fold and 2.6-fold in comparison to the negative control, respectively. Additionally, a shift toward a major production of exopolysaccharides was found coupled with a major production of both intracellular and extracellular reactive oxygen species. (iii) Lastly, detachment was generally promoted. In general, the L. racemosa extract had a higher bioactivity at lower concentrations than the B. cylindrica extract. Overall, our data showed a reduction in cells/conidia adhesion under B. cylindrica and L. racemosa exposure, followed by an increase of exopolysaccharides during biofilm maturation and a variable effect on biofilm dispersal. In conclusion, extracts either inhibited or enhanced biofilm development, and this effect depended on both the microbial taxon and biofilm formation step. eng
dc.language.iso eng
dc.publisher Basel : MDPI AG
dc.relation.ispartofseries International Journal of Molecular Sciences 20 (2019), Nr. 14
dc.rights CC BY 4.0 Unported
dc.subject antibiofilm activity eng
dc.subject biofilm promotion eng
dc.subject mangrove extract eng
dc.subject non-lethal concentration eng
dc.subject.ddc 580 | Pflanzen (Botanik) ger
dc.title Promoting beneficial and inhibiting undesirable biofilm formation with mangrove extracts
dc.type article
dc.type Text
dc.relation.issn 16616596
dc.bibliographicCitation.volume 20
dc.bibliographicCitation.firstPage 3549
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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