dc.identifier.uri |
http://dx.doi.org/10.15488/8806 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/8859 |
|
dc.contributor.author |
Glasenapp, Yvana
|
|
dc.contributor.author |
Catto, Cristina
|
|
dc.contributor.author |
Villa, Federica
|
|
dc.contributor.author |
Saracchi, Marco
|
|
dc.contributor.author |
Cappitelli, Francesca
|
|
dc.contributor.author |
Papenbrock, Jutta
|
|
dc.date.accessioned |
2019-12-11T16:44:50Z |
|
dc.date.available |
2019-12-11T16:44:50Z |
|
dc.date.issued |
2019 |
|
dc.identifier.citation |
Glasenapp, Y.; Catto, C.; Villa, F.; Saracchi, M.; Cappitelli, F.; Papenbrock, J.: Promoting beneficial and inhibiting undesirable biofilm formation with mangrove extracts. In: International Journal of Molecular Sciences 20 (2019), Nr. 14, 3549. DOI: https://doi.org/10.3390/ijms20143549 |
|
dc.description.abstract |
The extracts of two mangrove species, Bruguiera cylindrica and Laguncularia racemosa, have been analyzed at sub-lethal concentrations for their potential to modulate biofilm cycles (i.e., adhesion, maturation, and detachment) on a bacterium, yeast, and filamentous fungus. Methanolic leaf extracts were also characterized, and MS/MS analysis has been used to identify the major compounds. In this study, we showed the following. (i) Adhesion was reduced up to 85.4% in all the models except for E. coli, where adhesion was promoted up to 5.10-fold. (ii) Both the sum and ratio of extracellular polysaccharides and proteins in mature biofilm were increased up to 2.5-fold and 2.6-fold in comparison to the negative control, respectively. Additionally, a shift toward a major production of exopolysaccharides was found coupled with a major production of both intracellular and extracellular reactive oxygen species. (iii) Lastly, detachment was generally promoted. In general, the L. racemosa extract had a higher bioactivity at lower concentrations than the B. cylindrica extract. Overall, our data showed a reduction in cells/conidia adhesion under B. cylindrica and L. racemosa exposure, followed by an increase of exopolysaccharides during biofilm maturation and a variable effect on biofilm dispersal. In conclusion, extracts either inhibited or enhanced biofilm development, and this effect depended on both the microbial taxon and biofilm formation step. |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Basel : MDPI AG |
|
dc.relation.ispartofseries |
International Journal of Molecular Sciences 20 (2019), Nr. 14 |
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dc.rights |
CC BY 4.0 Unported |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
|
dc.subject |
antibiofilm activity |
eng |
dc.subject |
biofilm promotion |
eng |
dc.subject |
mangrove extract |
eng |
dc.subject |
non-lethal concentration |
eng |
dc.subject.ddc |
580 | Pflanzen (Botanik)
|
ger |
dc.title |
Promoting beneficial and inhibiting undesirable biofilm formation with mangrove extracts |
|
dc.type |
Article |
|
dc.type |
Text |
|
dc.relation.issn |
16616596 |
|
dc.relation.doi |
https://doi.org/10.3390/ijms20143549 |
|
dc.bibliographicCitation.volume |
20 |
|
dc.bibliographicCitation.firstPage |
3549 |
|
dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
|