Auflistung Naturwissenschaftliche Fakultät nach Autor/in "6de0e533-6052-4a91-856f-eacad46f6cd4"

Auflistung Naturwissenschaftliche Fakultät nach Autor/in "6de0e533-6052-4a91-856f-eacad46f6cd4"

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  • AnnoTALE: Bioinformatics tools for identification, annotation, and nomenclature of TALEs from Xanthomonas genomic sequences 
    Grau, Jan; Reschke, Maik; Erkes, Annett; Streubel, Jana; Morgan, Richard D.; Wilson, Geoffrey G.; Koebnik, Ralf; Boch, Jens (London : Nature Publishing Group, 2016)
    Transcription activator-like effectors (TALEs) are virulence factors, produced by the bacterial plant-pathogen Xanthomonas, that function as gene activators inside plant cells. Although the contribution of individual TALEs ...
  • Assembling highly repetitive Xanthomonas TALomes using Oxford Nanopore sequencing 
    Erkes, Annett; Grove, René P.; Žarković, Milena; Krautwurst, Sebastian; Koebnik, Ralf; Morgan, Richard D.; Wilson, Geoffrey G.; Hölzer, Martin; Marz, Manja; Boch, Jens; Grau, Jan (London : BioMed Central, 2023)
    Background: Most plant-pathogenic Xanthomonas bacteria harbor transcription activator-like effector (TALE) genes, which function as transcriptional activators of host plant genes and support infection. The entire repertoire ...
  • Cytoplasmic Injection of Zygotes to Genome Edit Naturally Occurring Sequence Variants Into Bovine Embryos 
    Wei, Jingwei; Brophy, Brigid; Cole, Sally-Ann; Moormann, Jannis; Boch, Jens; Laible, Gӧtz (Lausanne : Frontiers Media, 2022)
    Genome editing provides opportunities to improve current cattle breeding strategies through targeted introduction of natural sequence variants, accelerating genetic gain. This can be achieved by harnessing homology-directed ...
  • Development of TALE-adenine base editors in plants 
    Zhang, Dingbo; Boch, Jens (Oxford : Wiley-Blackwell, 2023)
    Base editors enable precise nucleotide changes at targeted genomic loci without requiring double-stranded DNA breaks or repair templates. TALE-adenine base editors (TALE-ABEs) are genome editing tools, composed of a ...
  • Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations 
    Streubel, Jana; Baum, Heidi; Grau, Jan; Stuttman, Johannes; Boch, Jens (San Francisco, CA : Public Library of Science, 2017)
    Plant-pathogenic Xanthomonas bacteria inject transcription activator-like effector proteins (TALEs) into host cells to specifically induce transcription of plant genes and enhance susceptibility. Although the DNA-binding ...
  • Epigenetic features improve TALE target prediction 
    Erkes, Annett; Mücke, Stefanie; Reschke, Maik; Boch, Jens; Grau, Jan (London : BioMed Central, 2021)
    Background: The yield of many crop plants can be substantially reduced by plant-pathogenic Xanthomonas bacteria. The infection strategy of many Xanthomonas strains is based on transcription activator-like effectors (TALEs), ...
  • Evolution of Transcription Activator-Like Effectors in Xanthomonas oryzae 
    Erkes, Annett; Reschke, Maik; Boch, Jens; Grau, Jan (Oxford : Oxford University Press, 2017)
    Transcription activator-like effectors (TALEs) are secreted by plant-pathogenic Xanthomonas bacteria into plant cells where they act as transcriptional activators and, hence, are major drivers in reprogramming the plant ...
  • Integrating Science on Xanthomonas and Xylella for Integrated Plant Disease Management 
    Costa, Joana; Pothier, Joël F.; Boch, Jens; Stefani, Emilio; Koebnik, Ralf (Basel : MDPI, 2023)
    [No abstract available]
  • PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting 
    Erkes, Anett; Mücke, Stefanie; Reschke, Maik; Boch, Jens; Grau, Jan (San Francisco, CA : Public Library of Science (PLoS), 2019)
    Plant-pathogenic Xanthomonas bacteria secrete transcription activator-like effectors (TALEs) into host cells, where they act as transcriptional activators on plant target genes to support bacterial virulence. TALEs have a ...
  • Production of light-coloured, low heat-absorbing Holstein Friesian cattle by precise embryo-mediated genome editing 
    Wei, Jingwei; Brophy, Brigid; Cole, Sally-Ann; Leath, Shane; Oback, Björn; Boch, Jens; Wells, David N.; Laible, Götz (Collingwood : CSIRO, 2024)
    Context. Genome editing enables the introduction of beneficial sequence variants into the genomes of animals with high genetic merit in a single generation. This can be achieved by introducing variants into primary cells ...
  • Removing the major allergen Bra j I from brown mustard (Brassica juncea) by CRISPR/Cas9 
    Assou, Juvenal; Zhang, Dingbo; Roth, Kristian D. R.; Steinke, Stephan; Hust, Michael; Reinard, Thomas; Winkelmann, Traud; Boch, Jens (Oxford [u.a.] : Wiley-Blackwell, 2021)
    Food allergies are a major health issue worldwide. Modern breeding techniques such as genome editing via CRISPR/Cas9 have the potential to mitigate this by targeting allergens in plants. This study addressed the major ...
  • Rice breeding in the new era: Comparison of useful agronomic traits 
    Hernández-Soto, Alejandro; Echeverría-Beirute, Fabián; Abdelnour-Esquivel, Ana; Valdez-Melara, Marta; Boch, Jens; Gatica-Arias, Andres (Amsterdam [u.a.] : Elsevier, 2021)
    Understanding agronomic traits at a genetic level enables the leveraging of this knowledge to produce crops that are more productive and resilient, have better quality and are adjusted for consumer preferences. In the last ...
  • The barley HvSTP13GR mutant triggers resistance against biotrophic fungi 
    Skoppek, Caroline Ines; Punt, Wilko; Heinrichs, Marleen; Ordon, Frank; Wehner, Gwendolin; Boch, Jens; Streubel, Jana (Oxford [u.a.] : Wiley-Blackwell, 2021)
    High-yielding and stress-resistant crops are essential to ensure future food supply. Barley is an important crop to feed livestock and to produce malt, but the annual yield is threatened by pathogen infections. Pathogens ...
  • Transcriptional Reprogramming of Rice Cells by Xanthomonas oryzae TALEs 
    Mücke, Stefanie; Reschke, Maik; Erkes, Annett; Schwietzer, Claudia-Alice; Becker, Sebastian; Streubel, Jana; Morgan, Richard D.; Wilson, Geoffrey G.; Grau, Jan; Boch, Jens (Lausanne : Frontiers Media, 2019)
    Rice-pathogenic Xanthomonas oryzae bacteria cause severe harvest loss and challenge a stable food supply. The pathogen virulence relies strongly on bacterial TALE (transcription activator-like effector) proteins that ...
  • Transgenic Expression of the Anti-parasitic Factor TEP1 in the Malaria Mosquito Anopheles gambiae 
    Volohonsky, Gloria; Hopp, Ann-Katrin; Saenger, Melanie; Soichot, Julien; Scholze, Heidi; Boch, Jens; Blandin, Stephanie A.; Marois, Eric (San Francisco, CA : Public Library of Science, 2017)
    Mosquitoes genetically engineered to be resistant to Plasmodium parasites represent a promising novel approach in the fight against malaria. The insect immune system itself is a source of anti-parasitic genes potentially ...

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