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dc.identifier.uri http://dx.doi.org/10.15488/749
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/773
dc.contributor.author Ruffert, Christine
dc.date.accessioned 2016-11-29T09:28:10Z
dc.date.available 2016-11-29T09:28:10Z
dc.date.issued 2016
dc.identifier.citation Ruffert, Christine: Magnetic bead-magic bullet. In: Micromachines 7 (2016), Nr. 2, 21. DOI: http://dx.doi.org/10.3390/mi7020021
dc.description.abstract Microfluidics is assumed to be one of the leading and most promising areas of research since the early 1990s. In microfluidic systems, small spherical magnetic particles with superparamagnetic properties, called magnetic beads, play an important role in the design of innovative methods and tools, especially in bioanalysis and medical sciences. The intention of this review paper is to address main aspects from the state-of-the-art in the area of magnetic bead research, while demonstrating the broad variety of applications and the huge potential to solve fundamental biological and medical problems in the fields of diagnostics and therapy. Basic issues and demands related to the fabrication of magnetic particles and physical properties of nanosize magnets are discussed in Section 2. Of main interest are the control and adjustment of the nanoparticles’ properties and the availability of adequate approaches for particle detection via their magnetic field. Section 3 presents an overview of magnetic bead applications in nanomedicine. In Section 4, practical aspects of sample manipulation and separation employing magnetic beads are described. Finally, the benefits related to the use of magnetic bead-based microfluidic systems are summarized, illustrating ongoing questions and open tasks to be solved on the way to an approaching microfluidic age. eng
dc.description.sponsorship DFG
dc.language.iso eng
dc.publisher Basel : MDPI AG
dc.relation.ispartofseries Micromachines 7 (2016), Nr. 2
dc.rights CC BY-NC-SA 4.0
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject Bioanalysis eng
dc.subject Detection eng
dc.subject Lab-on-a-chip eng
dc.subject magnetic bead eng
dc.subject microfluidics eng
dc.subject Nanomedicine eng
dc.subject Nanoparticle eng
dc.subject Separation eng
dc.subject Singleplexing eng
dc.subject Superparamagnetism eng
dc.subject Diagnosis eng
dc.subject Error detection eng
dc.subject Fluidic devices eng
dc.subject Magnetism eng
dc.subject Medical nanotechnology eng
dc.subject Medical problems eng
dc.subject Microfluidics eng
dc.subject Nanoparticles eng
dc.subject Separation eng
dc.subject Superparamagnetism eng
dc.subject Bioanalysis eng
dc.subject Control and adjustment eng
dc.subject Innovative method eng
dc.subject Magnetic beads eng
dc.subject Micro fluidic system eng
dc.subject.ddc 620 | Ingenieurwissenschaften und Maschinenbau ger
dc.title Magnetic bead-magic bullet
dc.type article
dc.type Text
dc.relation.issn 2072-666X
dc.relation.doi http://dx.doi.org/10.3390/mi7020021
dc.bibliographicCitation.issue 2
dc.bibliographicCitation.volume 7
dc.bibliographicCitation.firstPage 21
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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