dc.identifier.uri |
http://dx.doi.org/10.15488/606 |
|
dc.identifier.uri |
http://www.repo.uni-hannover.de/handle/123456789/630 |
|
dc.contributor.author |
Ullmann, Berit
|
|
dc.contributor.author |
Reifenrath, Janin
|
|
dc.contributor.author |
Dziuba, Dina
|
|
dc.contributor.author |
Seitz, Jan-Marten
|
|
dc.contributor.author |
Bormann, Dirk
|
|
dc.contributor.author |
Meyer-Lindenberg, Andrea
|
|
dc.date.accessioned |
2016-10-31T13:38:59Z |
|
dc.date.available |
2016-10-31T13:38:59Z |
|
dc.date.issued |
2011 |
|
dc.identifier.citation |
Ullmann, B.; Reifenrath, J.; Dziuba, D.; Seitz, Jan-Marten; Bormann, Dirk et al.: In vivo degradation behavior of the magnesium alloy land442 in rabbit tibiae. In: Materials 4 (2011), Nr. 12, S. 2197-2218. DOI: http://dx.doi.org/10.3390/ma4122197 |
|
dc.description.abstract |
In former studies the magnesium alloy LAE442 showed promising in vivo degradation behavior and biocompatibility. However, reproducibility might be enhanced by replacement of the rare earth composition metal "E" by only a single rare earth element. Therefore, it was the aim of this study to examine whether the substitution of "E" by neodymium ("Nd") had an influence on the in vivo degradation rate. LANd442 implants were inserted into rabbit tibiae and rabbits were euthanized after 4, 8, 13 and 26 weeks postoperatively. In vivo μCT was performed to evaluate the in vivo implant degradation behaviour by calculation of implant volume, density true 3-D thickness and corrosion rates. Additionally, weight loss, type of corrosion and mechanical stability were appraised by SEM/EDS-analysis and three-point bending tests. Implant volume, density and true 3-D thickness decreased over time, whereas the variance of the maximum diameters within an implant as well as the corrosion rate and weight loss increased. SEM examination revealed mainly pitting corrosion after 26 weeks. The maximum bending forces decreased over time. |
eng |
dc.description.sponsorship |
DFG/CRC/599 |
|
dc.language.iso |
eng |
|
dc.publisher |
Basel : MDPI AG |
|
dc.relation.ispartofseries |
Materials 4 (2011), Nr. 12 |
|
dc.rights |
CC BY-NC-SA 3.0 Unported |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-sa/3.0/ |
|
dc.subject |
μ-Computed tomography |
eng |
dc.subject |
Animal model |
eng |
dc.subject |
Biodegradation |
eng |
dc.subject |
Magnesium alloy |
eng |
dc.subject |
Mechanical stability |
eng |
dc.subject |
Animal model |
eng |
dc.subject |
Bending force |
eng |
dc.subject |
Degradation behaviours |
eng |
dc.subject |
Rare earth compositions |
eng |
dc.subject |
Reproducibilities |
eng |
dc.subject |
Sem examinations |
eng |
dc.subject |
Three-point bending test |
eng |
dc.subject |
Weight loss |
eng |
dc.subject |
Biocompatibility |
eng |
dc.subject |
Biodegradation |
eng |
dc.subject |
Computerized tomography |
eng |
dc.subject |
Corrosion rate |
eng |
dc.subject |
Degradation |
eng |
dc.subject |
Mechanical stability |
eng |
dc.subject |
Pitting |
eng |
dc.subject |
Magnesium alloys |
eng |
dc.subject.ddc |
600 | Technik
|
ger |
dc.subject.ddc |
624 | Ingenieurbau und Umwelttechnik
|
ger |
dc.title |
In vivo degradation behavior of the magnesium alloy land442 in rabbit tibiae |
|
dc.type |
Article |
|
dc.type |
Text |
|
dc.relation.issn |
1996-1944 |
|
dc.relation.doi |
http://dx.doi.org/10.3390/ma4122197 |
|
dc.bibliographicCitation.issue |
12 |
|
dc.bibliographicCitation.volume |
4 |
|
dc.bibliographicCitation.firstPage |
2197 |
|
dc.bibliographicCitation.lastPage |
2218 |
|
dc.description.version |
publishedVersion |
|
tib.accessRights |
frei zug�nglich |
|