Automation of a test bench for accessing the bendability of electrospun vascular grafts

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dc.identifier.uri Bensch, Martin Müller, Marc Bode, Michael Glasmacher, Birgit 2019-09-03T11:52:13Z 2019-09-03T11:52:13Z 2016
dc.identifier.citation Bensch, M.; Müller, M.; Bode, M.; Glasmacher, B.: Automation of a test bench for accessing the bendability of electrospun vascular grafts. In: Current Directions in Biomedical Engineering 2 (2016), Nr. 1, S. 307-310. DOI:
dc.description.abstract One of the greatest challenges in cardiovascular tissue engineering is to develop vascular grafts with properties similar to autologous vessels. A promising approach is the fabrication of scaffolds from biodegradable polymers by electrospinning. Unstructured vascular subs possess a weak dimensional stability resulting in lumen collapse when subjected to bending stress. In order to examine different structured grafts, a standardised test method is required. A manual test method, designed in a former study, was adopted in terms of standardisation and automation. Therefore, a control system was programmed to regulate the required electronics. The electronic circuit was then developed and put into service. To fix samples into the test bench a new sample holder and a new collector for electrospinning were designed. Subsequently, a validation showed the new systems' improved functionality compared to the former test bench. The samples were manufactured with the new collector. They could be fixed to the sample holder with high repeatability. The demand for vascular grafts with biological and mechanical properties similar to autologous vessels requires a standardised test method to examine bendability. The new test system enables the scaffolds to be examined regarding bendability with low personal expense and a simultaneously high degree of reproducibility. In addition, the new collector geometry can be easily adapted to higher or lower inner diameters. Hence, a new sample geometry was developed within this work. eng
dc.language.iso eng
dc.publisher Berlin : Walter de Gruyter
dc.relation.ispartofseries Current Directions in Biomedical Engineering 2 (2016), Nr. 1
dc.rights CC BY-NC-ND 4.0 Unported
dc.subject Bendability eng
dc.subject Biodegradable polymers eng
dc.subject Electrospinning eng
dc.subject Test bench eng
dc.subject Tissue engineering eng
dc.subject Vascular grafts eng
dc.subject.ddc 570 | Biowissenschaften, Biologie ger
dc.title Automation of a test bench for accessing the bendability of electrospun vascular grafts eng
dc.type article
dc.type Text
dc.relation.issn 2364-5504
dc.bibliographicCitation.issue 1
dc.bibliographicCitation.volume 2
dc.bibliographicCitation.firstPage 307
dc.bibliographicCitation.lastPage 310
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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