Many optical modalities are being investigated, applied, and further developed for non-invasive analysis and sensing in the life sciences. Often, the combination of two or more modalities is required for in depth analysis because of the complexity of the study objects and questions in this field. The work presents multimodal sensing concepts for applications ranging from non-invasive quantification of biomolecules in the living organism to supporting medical diagnosis showing the combined capabilities of Raman spectroscopy, optical coherence tomography, and optoacoustics
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