p-BioSPRE-an information and communication technology framework for transnational biomaterial sharing and access

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dc.identifier.uri http://dx.doi.org/10.15488/475
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/499
dc.contributor.author Weiler, Gabriele
dc.contributor.author Schröder, Christina
dc.contributor.author Schera, Fatima
dc.contributor.author Dobkowicz, Matthias
dc.contributor.author Kiefer, Stephan
dc.contributor.author Heidtke, Karsten R.
dc.contributor.author Hanold, Stefanie
dc.contributor.author Nwankwo, Iheanyi
dc.contributor.author Forgo, Nikolaus
dc.contributor.author Stanulla, Martin
dc.contributor.author Eckert, Cornelia
dc.contributor.author Graf, Norbert
dc.date.accessioned 2016-08-31T09:19:33Z
dc.date.available 2016-08-31T09:19:33Z
dc.date.issued 2014
dc.identifier.citation Weiler, Gabriele; Schroder, Christina; Schera, Fatima; Dobkowicz, Matthias; Kiefer, Stephan et al.: p-BioSPRE-an information and communication technology framework for transnational biomaterial sharing and access. In: Ecancermedicalscience 8 (2014), 401. DOI: http://dx.doi.org/10.3332/ecancer.2014.401
dc.description.abstract Biobanks represent key resources for clinico-genomic research and are needed to pave the way to personalised medicine. To achieve this goal, it is crucial that scientists can securely access and share high-quality biomaterial and related data. Therefore, there is a growing interest in integrating biobanks into larger biomedical information and communication technology (ICT) infrastructures. The European project p-medicine is currently building an innovative ICT infrastructure to meet this need. This platform provides tools and services for conducting research and clinical trials in personalised medicine. In this paper, we describe one of its main components, the biobank access framework p-BioSPRE (p-medicine Biospecimen Search and Project Request Engine). This generic framework enables and simplifies access to existing biobanks, but also to offer own biomaterial collections to research communities, and to manage biobank specimens and related clinical data over the ObTiMA Trial Biomaterial Manager. p-BioSPRE takes into consideration all relevant ethical and legal standards, e.g., safeguarding donors’ personal rights and enabling biobanks to keep control over the donated material and related data. The framework thus enables secure sharing of biomaterial within open and closed research communities, while flexibly integrating related clinical and omics data. Although the development of the framework is mainly driven by user scenarios from the cancer domain, in this case, acute lymphoblastic leukaemia and Wilms tumour, it can be extended to further disease entities. eng
dc.description.sponsorship FP7/2007-2013/270089
dc.language.iso eng
dc.publisher Bristol : Cancer Intelligence
dc.relation.ispartofseries Ecancermedicalscience 8 (2014)
dc.rights CC BY 3.0
dc.rights.uri https://creativecommons.org/licenses/by/3.0/
dc.subject biobank access eng
dc.subject specimen management eng
dc.subject p-BioSPRE eng
dc.subject ObTiMA eng
dc.subject Trial Biomaterial Manager eng
dc.subject IDB eng
dc.subject p-biobank wrapper eng
dc.subject.ddc 340 | Recht ger
dc.title p-BioSPRE-an information and communication technology framework for transnational biomaterial sharing and access
dc.type article
dc.type Text
dc.relation.essn 1754-6605
dc.relation.doi http://dx.doi.org/10.3332/ecancer.2014.401
dc.bibliographicCitation.volume 8
dc.bibliographicCitation.firstPage 401
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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