dc.identifier.uri |
http://dx.doi.org/10.15488/3321 |
|
dc.identifier.uri |
http://www.repo.uni-hannover.de/handle/123456789/3351 |
|
dc.contributor.author |
Reinecke, Tobias
|
|
dc.contributor.author |
Walter, Johanna-Gabriela
|
|
dc.contributor.author |
Kobelt, Tim
|
|
dc.contributor.author |
Ahrens, André
|
|
dc.contributor.author |
Scheper, Thomas
|
|
dc.contributor.author |
Zimmermann, Stefan
|
|
dc.date.accessioned |
2018-05-18T10:17:59Z |
|
dc.date.available |
2018-05-18T10:17:59Z |
|
dc.date.issued |
2018 |
|
dc.identifier.citation |
Reinecke, T.; Walter, J.-G.; Kobelt, T.; Ahrens, A.; Scheper, T. et al.: Design and evaluation of split-ring resonators for aptamer-based biosensors. In: Journal of Sensors and Sensor Systems 7 (2018), Nr. 1, S. 101-111. DOI: https://doi.org/10.5194/jsss-7-101-2018 |
|
dc.description.abstract |
Split-ring resonators are electrical circuits, which enable highly sensitive readout of split capacity changes via a measurement of the shift in the resonance frequency. Thus, functionalization of the split allows the development of biosensors, where selective molecular binding causes a change in permittivity and therefore a change in split capacity. In this work, we present a novel approach using transmission line theory to describe the dependency between permittivity of the sample and resonance frequency. This theory allows the identification of all relevant parameters of a split-ring resonator and thus a target-oriented optimization process. Hereby all setup optimizations are verified with measurements. Subsequently, the split of a resonator is functionalized with aptamers and the sensor response is investigated. This preliminary experiment shows that introducing the target protein results in a shift in the resonance frequency caused by a permittivity change due to aptamer-mediated protein binding, which allows selective detection of the target protein. © Author(s) 2018. |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Göttingen : Copernicus GmbH |
|
dc.relation.ispartofseries |
Journal of Sensors and Sensor Systems 7 (2018), Nr. 1 |
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dc.rights |
CC BY 4.0 Unported |
|
dc.rights.uri |
https://creativecommons.org/licenses/by/4.0/ |
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dc.subject |
Split-ring resonator |
eng |
dc.subject |
electrical circuits |
eng |
dc.subject |
biosensor |
eng |
dc.subject |
transmission line theory |
eng |
dc.subject.ddc |
621,3 | Elektrotechnik, Elektronik
|
ger |
dc.title |
Design and evaluation of split-ring resonators for aptamer-based biosensors |
eng |
dc.type |
Article |
|
dc.type |
Text |
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dc.relation.issn |
2194-8771 |
|
dc.relation.doi |
https://doi.org/10.5194/jsss-7-101-2018 |
|
dc.bibliographicCitation.issue |
1 |
|
dc.bibliographicCitation.volume |
7 |
|
dc.bibliographicCitation.firstPage |
101 |
|
dc.bibliographicCitation.lastPage |
111 |
|
dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
|