Effectiveness of nonpharmacological secondary prevention of coronary heart disease

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dc.identifier.uri http://dx.doi.org/10.15488/3001
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/3031
dc.contributor.author Müller-Riemenschneider, Falk
dc.contributor.author Meinhard, Charlotte
dc.contributor.author Damm, Kathrin
dc.contributor.author Vauth, Christoph
dc.contributor.author Bockelbrink, Angelina
dc.contributor.author Greiner, Wolfgang
dc.contributor.author Willich, Stefan N.
dc.date.accessioned 2018-02-28T14:00:57Z
dc.date.available 2018-02-28T14:00:57Z
dc.date.issued 2010
dc.identifier.citation Müller-Riemenschneider, F.; Meinhard, C.; Damm, K.; Vauth, C.; Bockelbrink, A. et al.: Effectiveness of nonpharmacological secondary prevention of coronary heart disease. In: European Journal of Cardiovascular Prevention and Rehabilitation 17 (2010), Nr. 6, S. 688-700. DOI: https://doi.org/10.1097/HJR.0b013e32833a1c95
dc.description.abstract Aim: To summarize the current evidence with regard to the effectiveness of nonpharmacological secondary prevention strategies of coronary heart disease (CHD) and to investigate the comparative effectiveness of interventions of different categories, specific intervention components and the effectiveness in patient subgroups. Methods: A structured search of databases and manual search were conducted. Clinical trials and meta-analyses published between January 2003 and September 2008 were included if they targeted adults with CHD, had a follow-up of at least 12 months, and reported mortality, cardiac events or quality of life. Two researchers assessed eligibility and methodological quality, in which appropriate, pooled effect estimates were calculated and tested in sensitivity analyses. Results: Of 4798 publications 43 met the inclusion criteria. Overall study quality was satisfactory, but only about half of the studies reported mortality. Follow-up duration varied between 12 and 120 months. Despite substantial heterogeneity, there was strong evidence of intervention effectiveness overall. The evidence for exercise and multimodal interventions was more conclusive for reducing mortality, whereas psychosocial interventions seemed to be more effective in improving the quality of life. Rigorous studies investigating dietary and smoking cessation interventions, specific intervention components and important patient subgroups, were scarce. Conclusion: Nonpharmacological secondary prevention is safe and effective, with exercise and multimodal interventions reducing mortality most substantially. There is a lack of studies concerning dietary and smoking cessation interventions. In addition, intervention effectiveness in patient subgroups and of intervention components could not be evaluated conclusively. Future research should investigate these issues in rigorous studies with appropriate follow-up duration to improve the current poor risk factor control of CHD patients. © 2010 The European Society of Cardiology. eng
dc.language.iso eng
dc.publisher London : SAGE Publications Ltd.
dc.relation.ispartofseries European Journal of Cardiovascular Prevention and Rehabilitation 17 (2010), Nr. 6
dc.rights Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
dc.subject coronary heart disease eng
dc.subject meta-analysis eng
dc.subject secondary prevention eng
dc.subject systematic review eng
dc.subject unsaturated fatty acid eng
dc.subject article eng
dc.subject cardiovascular risk eng
dc.subject diet supplementation eng
dc.subject diet therapy eng
dc.subject dietary fiber eng
dc.subject exercise eng
dc.subject follow up eng
dc.subject genetic heterogeneity eng
dc.subject health program eng
dc.subject home care eng
dc.subject hospital care eng
dc.subject human eng
dc.subject intermethod comparison eng
dc.subject intervention study eng
dc.subject ischemic heart disease eng
dc.subject low fat diet eng
dc.subject medical research eng
dc.subject meta analysis (topic) eng
dc.subject mortality eng
dc.subject outcome assessment eng
dc.subject priority journal eng
dc.subject psychosocial care eng
dc.subject quality of life eng
dc.subject randomized controlled trial (topic) eng
dc.subject secondary prevention eng
dc.subject sensitivity analysis eng
dc.subject smoking cessation eng
dc.subject stress management eng
dc.subject systematic review eng
dc.subject therapy effect eng
dc.subject treatment indication eng
dc.subject Coronary Disease eng
dc.subject Diet eng
dc.subject Exercise eng
dc.subject Humans eng
dc.subject Psychotherapy eng
dc.subject Quality of Life eng
dc.subject Recurrence eng
dc.subject Risk Assessment eng
dc.subject Risk Factors eng
dc.subject Risk Reduction Behavior eng
dc.subject Secondary Prevention eng
dc.subject Smoking Cessation eng
dc.subject Treatment Outcome eng
dc.subject.ddc 610 | Medizin, Gesundheit ger
dc.title Effectiveness of nonpharmacological secondary prevention of coronary heart disease
dc.type article
dc.type Text
dc.relation.issn 0174-18267
dc.relation.doi https://doi.org/10.1097/HJR.0b013e32833a1c95
dc.bibliographicCitation.issue 6
dc.bibliographicCitation.volume 17
dc.bibliographicCitation.firstPage 688
dc.bibliographicCitation.lastPage 700
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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