dc.identifier.uri | http://dx.doi.org/10.15488/2473 | |
dc.identifier.uri | http://www.repo.uni-hannover.de/handle/123456789/2499 | |
dc.contributor.author | Kaspera, Rüdiger | |
dc.contributor.author | Krings, Ulrich | |
dc.contributor.author | Pescheck, Michael | |
dc.contributor.author | Sell, Dieter | |
dc.contributor.author | Schrader, Jens | |
dc.contributor.author | Berger, Ralf Günter | |
dc.date.accessioned | 2017-11-24T12:08:37Z | |
dc.date.available | 2017-11-24T12:08:37Z | |
dc.date.issued | 2005 | |
dc.identifier.citation | Kaspera, R.; Krings, U.; Pescheck, M.; Sell, D.; Schrader, J. et al.: Regio- and stereoselective fungal oxyfunctionalisation of limonenes. In: Zeitschrift für Naturforschung - Section C Journal of Biosciences 60 (2005), Nr. 5-6, S. 459-466. DOI: https://doi.org/10.1515/znc-2005-5-615 | |
dc.description.abstract | Selective transformations of limonene by asco- and basidiomycetes were investigated. On the shake flask scale, Penicillium citrinum hydrated R-(+)-limonene to α-terpineol [83% regioselectivity (rs), more than 80 mg l-1 product yield], and Gongronella butleri catalysed the terminal oxidation to yield perillyl alcohol (60% rs, 16 mg l-1). On the laboratory bioreactor scale, Penicillium digitatum produced a peak concentration of 506 mg α-terpineol l-1 in the fed-batch mode, equivalent to a theoretical yield of 67%, and no volatile by-products were found. Fusarium proliferatum transformed R-(+)-limonene enantiospecifically to cis-(+)-carveol (98.6% ee, more than 35 mg l-1 product yield) and S-(-)-limonene predominantly to trans-(-)-carveol (96.3% ee). Pleurotus sapidus selectively dehydrogenised the accumulating trans-(-)-carveol to the corresponding enantiopure R-(-)-carvone. The results show that a careful selection of strain and bioprocess parameters may improve both the yield and the optical purity of a desired product. | eng |
dc.language.iso | eng | |
dc.publisher | Berlin : De Gruyter | |
dc.relation.ispartofseries | Zeitschrift für Naturforschung - Section C Journal of Biosciences 60 (2005), Nr. 5-6 | |
dc.rights | CC BY-NC-ND 3.0 Unported | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ | |
dc.subject | Limonene | eng |
dc.subject | Oxyfunctionalisation | eng |
dc.subject | Stereoselectivity | eng |
dc.subject | cyclohexene derivative | eng |
dc.subject | limonene | eng |
dc.subject | terpene | eng |
dc.subject | article | eng |
dc.subject | Ascomycetes | eng |
dc.subject | Basidiomycetes | eng |
dc.subject | biotransformation | eng |
dc.subject | metabolism | eng |
dc.subject | oxidation reduction reaction | eng |
dc.subject | structure activity relation | eng |
dc.subject | Ascomycota | eng |
dc.subject | Basidiomycota | eng |
dc.subject | Biotransformation | eng |
dc.subject | Cyclohexenes | eng |
dc.subject | Oxidation-Reduction | eng |
dc.subject | Structure-Activity Relationship | eng |
dc.subject | Terpenes | eng |
dc.subject | Basidiomycota | eng |
dc.subject | Fusarium proliferatum | eng |
dc.subject | Gongronella butleri | eng |
dc.subject | Penicillium citrinum | eng |
dc.subject | Penicillium digitatum | eng |
dc.subject | Pleurotus | eng |
dc.subject | Pleurotus sapidus | eng |
dc.subject.ddc | 570 | Biowissenschaften, Biologie | ger |
dc.title | Regio- and stereoselective fungal oxyfunctionalisation of limonenes | |
dc.type | Article | |
dc.type | Text | |
dc.relation.essn | 1865-7125 | |
dc.relation.issn | 0939-5075 | |
dc.relation.doi | https://doi.org/10.1515/znc-2005-5-615 | |
dc.bibliographicCitation.issue | 5-6 | |
dc.bibliographicCitation.volume | 60 | |
dc.bibliographicCitation.firstPage | 459 | |
dc.bibliographicCitation.lastPage | 466 | |
dc.description.version | publishedVersion | |
tib.accessRights | frei zug�nglich |
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