Optimization of a test setup for examining blood damage caused by high shear forces

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dc.identifier.uri http://dx.doi.org/10.15488/201
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/223
dc.contributor.author Kortlepel, Rieke
dc.contributor.author Krolitzki, Benjamin
dc.contributor.author Müller, Marc
dc.contributor.author Glasmacher, Birgit
dc.date.accessioned 2016-02-02T12:03:16Z
dc.date.available 2016-02-02T12:03:16Z
dc.date.issued 2012-08-27
dc.identifier.citation Kortlepel, R.; Krolitzki, B.; Müller, M.; Glasmacher, Birgit: Optimization of a test setup for examining blood damage caused by high shear forces. In: Biomedical Engineering / Biomedizinische Technik 57 (2012), Nr. SI-1 Track-D. DOI: http://dx.doi.org/10.1515/bmt-2012-4362
dc.description.abstract If blood pumps are applied in the human body or extracorporeal, blood damage can be caused by shear forces that act on the blood during the delivery. For an accelerated development of blood pumps with help of simulations there is a need for reliable limit values for shear forces. To determine these limit values a shear force test setup was built at the Institute for Multiphase Processes. In the context of the presented master thesis the former test setup peripheral devices were evaluated, possible blood damage mechanisms were considered, blood analysis in different experiments to identify the blood damage caused by different elements were made and peripheral devices were replaced. At the same time the shear chamber was constructional reengineered in a project thesis [1]. We were able to show, that in former works the blood damage caused by test setup peripheral devices had heterodyned the results. Finally the test setup was rebuilt with the results and a test was made. Two findings of the thesis are a reduction of about 60% of the number of components in the blood-conveying tube system and an application of a new fluid seal. eng
dc.description.sponsorship SFB-TR37 - Q2
dc.description.sponsorship SFB-TR37 - B4
dc.description.sponsorship EXC 62/1
dc.language.iso eng
dc.publisher Berlin : Walter de Gruyter
dc.relation.ispartofseries Biomedical Engineering / Biomedizinische Technik 57 (2012), Nr. SI-1 Track-D
dc.rights Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
dc.subject biomaterial eng
dc.subject biocompatibility eng
dc.subject blood pump eng
dc.subject blood damage eng
dc.subject human body eng
dc.subject.classification Konferenzschrift ger
dc.subject.ddc 600 | Technik ger
dc.subject.ddc 610 | Medizin, Gesundheit ger
dc.title Optimization of a test setup for examining blood damage caused by high shear forces eng
dc.type article
dc.type Text
dc.relation.essn 1862-278X
dc.relation.doi http://dx.doi.org/10.1515/bmt-2012-4362
dc.bibliographicCitation.issue SI-1 Track-D
dc.bibliographicCitation.volume 57
dc.bibliographicCitation.firstPage 569
dc.bibliographicCitation.lastPage 599
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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