Effect of patulin from penicillium vulpinum on the activity of Glutathione-S-Transferase and selected antioxidative enzymes in Maize

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dc.identifier.uri http://dx.doi.org/10.15488/1943
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/1968
dc.contributor.author Ismaiel, Ahmed A.
dc.contributor.author Papenbrock, Jutta
dc.date.accessioned 2017-09-22T11:47:56Z
dc.date.available 2017-09-22T11:47:56Z
dc.date.issued 2017
dc.identifier.citation Ismaiel, A.A.; Papenbrock, J.: Effect of patulin from penicillium vulpinum on the activity of Glutathione-S-Transferase and selected antioxidative enzymes in Maize. In: International Journal of Environmental Research and Public Health 14 (2017), Nr. 7, No. 825. DOI: https://doi.org/10.3390/ijerph14070825
dc.description.abstract The mycotoxin patulin (PAT) was purified from Penicillium vulpinum CM1 culture that has been isolated from a soil cultivated with maize. The effect of PAT and of a fungal culture filtrate on the activities of glutathione-S-transferase (GST) and some antioxidant enzymes viz. ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR) and monodehydroascorbate reductase (MDHAR) was investigated in roots and shoots of 8-day-old maize seedlings. PAT and culture filtrate caused significant reduction effects in a dose-related manner on the total GST activity. Upon application of the high PAT concentration (25 μg·mL−1) and of the concentrated fungal filtrate (100%, v/v), the reduction in GST activity of roots was 73.8–76.0% and of shoots was 60–61.7%. Conversely, significant increases in the activities of antioxidant enzymes were induced. Application of 25 μg·PAT·mL−1 increased APX, GR, DHAR, and MDHAR activity of root by 2.40-, 2.00-, 1.24-, and 2.16-fold, respectively. In shoots, the enzymatic activity was increased by 1.57-, 1.45-, 1.45-, and 1.61-fold, respectively. Similar induction values of the enzymatic activity were obtained upon application of the concentrated fungal filtrate. This is the first report describing the response of GST and antioxidant enzyme activities of plant cells to PAT toxicity. eng
dc.description.sponsorship DFG/PA 764/19-1
dc.language.iso eng
dc.publisher Basel : MDPI AG
dc.relation.ispartofseries International Journal of Environmental Research and Public Health 14 (2017), Nr. 7
dc.rights CC BY 4.0 Unported
dc.rights.uri https://creativecommons.org/licenses/by/4.0
dc.subject Penicillium vulpinum eng
dc.subject Zea mays eng
dc.subject Antioxidants eng
dc.subject Glutathione-S-transferase (GST) eng
dc.subject Maize eng
dc.subject Patulin (PAT) eng
dc.subject Penicillium vulpinum eng
dc.subject.ddc 580 | Pflanzen (Botanik) ger
dc.title Effect of patulin from penicillium vulpinum on the activity of Glutathione-S-Transferase and selected antioxidative enzymes in Maize
dc.type article
dc.type Text
dc.relation.issn 16617827
dc.relation.doi https://doi.org/10.3390/ijerph14070825
dc.bibliographicCitation.issue 7
dc.bibliographicCitation.volume 14
dc.bibliographicCitation.firstPage 825
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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