dc.identifier.uri |
http://dx.doi.org/10.15488/13815 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/13927 |
|
dc.contributor.author |
Krahe, Nina‐Katharina
|
|
dc.contributor.author |
Berger, Ralf G.
|
|
dc.contributor.author |
Kahlert, Lukas
|
|
dc.contributor.author |
Ersoy, Franziska
|
|
dc.date.accessioned |
2023-06-06T09:09:37Z |
|
dc.date.available |
2023-06-06T09:09:37Z |
|
dc.date.issued |
2021 |
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dc.identifier.citation |
Krahe, N.-K.; Berger, R.G.; Kahlert, L.; Ersoy, F.: Co-Oxidative Transformation of Piperine to Piperonal and 3,4-Methylenedioxycinnamaldehyde by a Lipoxygenase from Pleurotus sapidus. In: ChemBioChem : an official journal of the EFMC 22 (2021), Nr. 19, S. 2857-2861. DOI: https://doi.org/10.1002/cbic.202100183 |
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dc.description.abstract |
The valuable aroma compound piperonal with its vanilla-like olfactory properties is of high interest for the fragrance and flavor industry. A lipoxygenase (LOXPsa1) of the basidiomycete Pleurotus sapidus was identified to convert piperine, the abundant pungent principle of black pepper (Piper nigrum), to piperonal and a second volatile product, 3,4-methylenedioxycinnamaldehyde, with a vanilla-like odor through an alkene cleavage. The reaction principle was co-oxidation, as proven by its dependence on the presence of linoleic or α-linolenic acid, common substrates of lipoxygenases. Optimization of the reaction conditions (substrate concentrations, reaction temperature and time) led to a 24-fold and 15-fold increase of the piperonal and 3,4-methylenedioxycinnamaldehyde concentration using the recombinant enzyme. Monokaryotic strains showed different concentrations of and ratios between the two reaction products. |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Weinheim : Wiley-VCH |
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dc.relation.ispartofseries |
ChemBioChem : an official journal of the EFMC 22 (2021), Nr. 19 |
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dc.rights |
CC BY 4.0 Unported |
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dc.rights.uri |
https://creativecommons.org/licenses/by/4.0 |
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dc.subject |
biotransformations |
eng |
dc.subject |
cleavage reactions |
eng |
dc.subject |
co-oxidation |
eng |
dc.subject |
lipoxygenase |
eng |
dc.subject |
piperonal |
eng |
dc.subject.ddc |
540 | Chemie
|
ger |
dc.title |
Co-Oxidative Transformation of Piperine to Piperonal and 3,4-Methylenedioxycinnamaldehyde by a Lipoxygenase from Pleurotus sapidus |
eng |
dc.type |
Article |
|
dc.type |
Text |
|
dc.relation.essn |
1439-7633 |
|
dc.relation.issn |
1439-4227 |
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dc.relation.doi |
https://doi.org/10.1002/cbic.202100183 |
|
dc.bibliographicCitation.issue |
19 |
|
dc.bibliographicCitation.volume |
22 |
|
dc.bibliographicCitation.firstPage |
2857 |
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dc.bibliographicCitation.lastPage |
2861 |
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dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
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