The vinylogous Mukaiyama aldol reaction (VMAR) in natural product synthesis

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dc.identifier.uri Kalesse, Markus Cordes, Martin Symkenberg, Gerrit Lu, Hai-Hua 2015-11-19T13:00:01Z 2015-11-19T13:00:01Z 2014-03-05
dc.identifier.citation Kalesse, Markus; Cordes, Martin; Symkenberg, Gerrit; Lu, Hai-Hua: The vinylogous Mukaiyama aldol reaction (VMAR) in natural product synthesis. In: Natural Product Reports 31 (2014), Nr. 4, S. 563-594. DOI:
dc.description.abstract The vinylogous Mukaiyama aldol reaction (VMAR) allows efficient access to larger segments for complex natural product synthesis, primarily polyketides, through the construction of vicinal hydroxyl and methyl groups as well as di and tri-substituted double bonds in one single operation. In this review, we will highlight stereoselective protocols that have been used in natural product synthesis and cluster them into the four groups that can be obtained from different silyl ketene acetals or enol ethers. At the beginning, an overview on different stereoselective VMARs is presented; disregarding their applications in total syntheses. eng
dc.language.iso eng eng
dc.publisher Cambridge : Royal Society of Chemistry
dc.relation.ispartofseries Natural Product Reports 31 (2014), Nr. 4
dc.rights Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
dc.subject 1st Total-Synthesis eng
dc.subject Synthesis eng
dc.subject Alga Constantinea-Simplex eng
dc.subject Lewis-Base Activation eng
dc.subject Stereocontrolled Total-Synthesis eng
dc.subject Enantioselective Total-Synthesis eng
dc.subject Silyl Ketene Acetals eng
dc.subject Sponge Tedania-Ignis eng
dc.subject Addition-Reactions eng
dc.subject Marine Sponge eng
dc.subject Scytophycin-C eng
dc.subject.ddc 540 | Chemie ger
dc.subject.ddc 570 | Biowissenschaften, Biologie ger
dc.title The vinylogous Mukaiyama aldol reaction (VMAR) in natural product synthesis eng
dc.type article
dc.type Text
dc.relation.essn 1460-4752
dc.relation.issn 0265-0568
dc.bibliographicCitation.issue 4
dc.bibliographicCitation.volume 31
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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