dc.identifier.uri |
http://dx.doi.org/10.15488/11594 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/11685 |
|
dc.contributor.author |
Sreemantula, Arun Kumar
|
eng |
dc.contributor.author |
Marchanka, Alexander
|
eng |
dc.date.accessioned |
2021-12-20T13:41:00Z |
|
dc.date.available |
2021-12-20T13:41:00Z |
|
dc.date.issued |
2020 |
|
dc.identifier.citation |
Sreemantula, A.K.; Marchanka, A.: Solid-state NMR spectroscopy for characterization of RNA and RNP complexes. In: Biochemical Society Transactions 48 (2020), Nr. 3, S. 1077-1087. DOI: https://doi.org/10.1042/BST20191080 |
eng |
dc.description.abstract |
Ribonucleic acids are driving a multitude of biological processes where they act alone or in complex with proteins (ribonucleoproteins, RNP). To understand these processes both structural and mechanistic information about RNA is necessary. Due to their conformational plasticity RNA pose a challenge for mainstream structural biology methods. Solid-state NMR (ssNMR) spectroscopy is an emerging technique that can be applied to biomolecular complexes of any size in close-to-native conditions. This review outlines recent methodological developments in ssNMR for structural characterization of RNA and protein–RNA complexes and provides relevant examples. |
eng |
dc.language.iso |
eng |
eng |
dc.publisher |
London : Portland Press |
|
dc.relation.ispartofseries |
Biochemical Society Transactions 48 (2020), Nr. 3 |
eng |
dc.rights |
Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. |
eng |
dc.subject |
method development |
eng |
dc.subject |
RNA structure |
eng |
dc.subject |
solid-state NMR |
eng |
dc.subject.ddc |
540 | Chemie
|
eng |
dc.title |
Solid-state NMR spectroscopy for characterization of RNA and RNP complexes |
eng |
dc.type |
Article |
eng |
dc.type |
Text |
eng |
dc.relation.essn |
1470-8752 |
|
dc.relation.issn |
0300-5127 |
|
dc.relation.doi |
10.1042/BST20191080 |
|
dc.bibliographicCitation.firstPage |
1077 |
|
dc.bibliographicCitation.lastPage |
1087 |
|
dc.description.version |
publishedVersion |
eng |
tib.accessRights |
frei zug�nglich |
eng |