High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar

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dc.identifier.uri http://dx.doi.org/10.15488/10990
dc.identifier.uri https://www.repo.uni-hannover.de/handle/123456789/11072
dc.contributor.author Schlottmann, Florian
dc.contributor.author Kirk, Ansgar T.
dc.contributor.author Allers, Maria
dc.contributor.author Bohnhorst, Alexander
dc.contributor.author Zimmermann, Stefan
dc.date.accessioned 2021-05-25T07:03:53Z
dc.date.available 2021-05-25T07:03:53Z
dc.date.issued 2020
dc.identifier.citation Schlottmann, F.; Kirk, A.T.; Allers, M.; Bohnhorst, A.; Zimmermann, S.: High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar. In: Journal of the American Society for Mass Spectrometry : JASMS online 31 (2020), Nr. 7, S. 1536-1543. DOI: https://doi.org/10.1021/jasms.0c00098
dc.description.abstract High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) are usually operated at an absolute pressure of 20 mbar reaching high reduced electric field strengths of up to 125 Td for controlled reaction kinetics. This significantly increases the linear range and limits chemical cross sensitivities. Furthermore, HiKE-IMS enables the ionization of compounds normally not detectable in ambient pressure IMS, such as benzene, due to new reaction pathways and the inhibition of clustering reactions. In addition, HiKE-IMS allows the observation of additional orthogonal parameters related to an increased ion temperature such as fragmentation and field-dependent ion mobility, which may help to separate compounds that have similar ion mobility under low field conditions. Aiming for a hand-held HiKE-IMS to carry its benefits into field applications, reducing size and power consumption of the vacuum system is necessary. In this work, we present a novel HiKE-IMS design entirely manufactured from standard printed circuit boards (PCB) and experimentally investigate the analytical performance in dependence of the operating pressure between 20 mbar and 40 mbar. Hereby, the limit of detection (LoD) for benzene in purified, dry air (1.4 ppmV water) improved from 7 ppbV at 20 mbar down to 1.8 ppbV at 40 mbar. Furthermore, adding 0.9 ppmV toluene the signal of the benzene B+ peak decreases by only 2 % at 40 mbar. Even in the presence of high relative humidity in the sample gas above 90 % or toluene concentrations of up to 20 ppmV, the LoD for benzene just increases to 9 ppbV at 40 mbar. eng
dc.language.iso eng
dc.publisher Washington, DC : ACS Publications
dc.relation.ispartofseries Journal of the American Society for Mass Spectrometry : JASMS online 31 (2020), Nr. 7
dc.rights Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden.
dc.subject Ion Mobility Spectrometers (HiKE-IMS) eng
dc.subject printed circuit boards (PCB) eng
dc.subject limit of detection (LoD) eng
dc.subject.ddc 530 | Physik ger
dc.title High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar
dc.type Article
dc.type Text
dc.relation.essn 1879-1123
dc.relation.issn 1044-0305
dc.relation.doi https://doi.org/10.1021/jasms.0c00098
dc.bibliographicCitation.issue 7
dc.bibliographicCitation.volume 31
dc.bibliographicCitation.firstPage 1536
dc.bibliographicCitation.lastPage 1543
dc.description.version acceptedVersion
tib.accessRights frei zug�nglich

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