Health-related quality of life questionnaires in lung cancer trials: A systematic literature review

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dc.identifier.uri Damm, Kathrin Roeske, Nicole Jacob, Christian 2017-01-27T07:49:20Z 2017-01-27T07:49:20Z 2013
dc.identifier.citation Damm, Kathrin; Roeske, Nicole; Jacob, C.: Health-related quality of life questionnaires in lung cancer trials: A systematic literature review. In: Health Economics Review 3 (2013), Nr. 1, 15. DOI:
dc.description.abstract Background: Lung cancer is one of the leading causes of cancer deaths. Treatment goals are the relief of symptoms and the increase of overall survival. With the rising number of treatment alternatives, the need for comparable assessments of health-related quality of life (HRQoL) parameters grows. The aim of this paper was to identify and describe measurement instruments applied in lung cancer patients under drug therapy. Methods: We conducted a systematic literature review at the beginning of 2011 using the electronic database Pubmed. Results: A total of 43 studies were included in the review. About 17 different measurement instruments were identified, including 5 generic, 5 cancer-specific, 4 lung cancer-specific and 3 symptom-specific questionnaires. In 29 studies at least 2 instruments were used. In most cases these were cancer and lung cancer-specific ones. The most frequently used instruments are the EORTC QLQ-C30 and its lung cancer modules LC13 or LC17. Only 5 studies combined (lung) cancer-specific questionnaires with generic instruments. Conclusions: The EORTC-C30 and EORTC-LC13 are the most frequently used health-related quality of life measurement instruments in pharmacological lung cancer trials. eng
dc.language.iso eng
dc.publisher Heidelberg : Springer Verlag
dc.relation.ispartofseries Health Economics Review 3 (2013), Nr. 1
dc.rights CC BY 2.0
dc.subject Health economics eng
dc.subject Health-related quality of life eng
dc.subject Lung cancer eng
dc.subject Questionnaires eng
dc.subject Utility measurement eng
dc.subject adenosine triphosphate eng
dc.subject amifostine eng
dc.subject carboplatin eng
dc.subject Chinese drug eng
dc.subject cisplatin eng
dc.subject docetaxel eng
dc.subject erlotinib eng
dc.subject etopofos eng
dc.subject etoposide eng
dc.subject excision repair cross complementing protein 1 eng
dc.subject gefitinib eng
dc.subject gemcitabine eng
dc.subject generic drug eng
dc.subject ifosfamide eng
dc.subject irinotecan eng
dc.subject megestrol acetate eng
dc.subject mitomycin eng
dc.subject.ddc 330 | Wirtschaft ger
dc.subject.ddc 610 | Medizin, Gesundheit ger
dc.title Health-related quality of life questionnaires in lung cancer trials: A systematic literature review
dc.type article
dc.type Text
dc.relation.issn 2191-1991
dc.bibliographicCitation.issue 1
dc.bibliographicCitation.volume 3
dc.bibliographicCitation.firstPage 15
dc.description.version publishedVersion
tib.accessRights frei zug�nglich

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