Simultaneous cancer control and diagnosis with magnetic nanohybrid materials

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dc.identifier.uri http://dx.doi.org/10.15488/1039
dc.identifier.uri http://www.repo.uni-hannover.de/handle/123456789/1063
dc.contributor.author Saadat, Reza
dc.contributor.author Renz, Franz
dc.date.accessioned 2017-01-12T08:35:34Z
dc.date.available 2017-01-12T08:35:34Z
dc.date.issued 2016
dc.identifier.citation Saadat, R.; Renz, F.: Simultaneous cancer control and diagnosis with magnetic nanohybrid materials. In: Beilstein Journal of Nanotechnology 7 (2016), Nr. 1, S. 121-125. DOI: http://dx.doi.org/10.3762/bjnano.7.14
dc.description.abstract Coated magnetite nanoparticles were linked to 68Ga complexes used in the positron emission tomography (PET) for a new technical approach to detect cancer tissue with radiopharmaceuticals. By substitution of the Ga isotope with an alpha emitter the same compound could be used for cancer treatment. Furthermore the nanoparticles were connected to pH-sensitive complexes, enabling a pH-controlled assembly/disassembly and therefore the spreading of the particles in the tissue. With this novel method of combining detection and treatment simultaneously, the amount of medical exposure could be minimized for the patient. The results demonstrate that magnetite nanoparticles can effectively be functionalized with PET isotopes and pH sensitive complexes in order to use them as a new type of radiopharmaceuticals. © 2016 Saadat and Renz. eng
dc.language.iso eng
dc.publisher Frankfurt am Main : Beilstein-Institut zur Forderung der Chemischen Wissenschaften
dc.relation.ispartofseries Beilstein Journal of Nanotechnology 7 (2016), Nr. 1
dc.rights CC BY 2.0 Unported
dc.rights.uri https://creativecommons.org/licenses/by/2.0/
dc.subject Biocompatible nanoparticles eng
dc.subject Cancer control eng
dc.subject Cancer diagnosis eng
dc.subject Magnetite nanoparticles eng
dc.subject Positron emission tomography eng
dc.subject Biocompatibility eng
dc.subject Diagnosis eng
dc.subject Diseases eng
dc.subject Isotopes eng
dc.subject Magnetite eng
dc.subject Magnetite nanoparticles eng
dc.subject Nanoparticles eng
dc.subject Patient treatment eng
dc.subject pH sensors eng
dc.subject Positrons eng
dc.subject Tissue eng
dc.subject Alpha emitters eng
dc.subject Biocompatible nanoparticles eng
dc.subject Cancer control eng
dc.subject Cancer diagnosis eng
dc.subject Controlled assembly eng
dc.subject Functionalized eng
dc.subject Nano-hybrid materials eng
dc.subject Positron emission tomography (PET) eng
dc.subject Positron emission tomography eng
dc.subject.ddc 620 | Ingenieurwissenschaften und Maschinenbau ger
dc.title Simultaneous cancer control and diagnosis with magnetic nanohybrid materials eng
dc.type Text
dc.type article
dc.relation.issn 2190-4286
dc.relation.doi https://doi.org/10.3762/bjnano.7.14
dc.bibliographicCitation.issue 1
dc.bibliographicCitation.volume 7
dc.bibliographicCitation.firstPage 121
dc.bibliographicCitation.lastPage 125
dc.description.version publishedVersion
tib.accessRights frei zug�nglich


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