dc.identifier.uri |
http://dx.doi.org/10.15488/10172 |
|
dc.identifier.uri |
https://www.repo.uni-hannover.de/handle/123456789/10244 |
|
dc.contributor.author |
Han, M.
|
|
dc.contributor.author |
Li, G.
|
|
dc.contributor.author |
Liu, Xiaowei
|
|
dc.contributor.author |
Li, A.
|
|
dc.contributor.author |
Mao, P.
|
|
dc.contributor.author |
Liu, P.
|
|
dc.contributor.author |
Li, H.
|
|
dc.date.accessioned |
2020-11-03T09:48:33Z |
|
dc.date.available |
2020-11-03T09:48:33Z |
|
dc.date.issued |
2019 |
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dc.identifier.citation |
Han, M.; Li G.; Liu, Xiaowei; Li A.; Mao, P. et al.: Phenolic Profile, Antioxidant Activity and Anti-proliferative Activity of Crabapple Fruits. In: Horticultural Plant Journal 5 (2019), Nr. 4, S. 155-163. DOI: https://doi.org/10.1016/j.hpj.2019.01.003 |
|
dc.description.abstract |
To explore the potential of crabapples as functional food, polyphenols in crabapples and ‘Fuji’ apples were extracted, and the phenolic profile, total polyphenols, antioxidant activity and anti-proliferative activity against several human cancer cells were determined. The results indicated that crabapple extracts have more abundant phenols and higher total polyphenols (from 4.46 to 46.63 mg GAE·g−1 DW) compared to ‘Fuji’ apples. Crabapple extracts possessed higher antioxidant activity than apple by DPPH and ABTS analysis. All fruit extracts exhibited inhibitory effects on proliferation in different cancer cells; however, crabapple extracts performed significantly better, with half inhibitory concentration (IC50) values varied from 48.34 µg·mL−1 to 974.81 µg·mL−1 for colon cancer cells SW480, 64.67–1 466.35 µg·mL−1 for stomach cancer cells BGC-803, 78.88–910.64 µg·mL−1 for esophageal cancer cells CaEs-17. Besides, the red crabapples had higher antioxidant activity and anti-proliferative activity than yellow fruits. These results showed that crabapples, especially red crabapples, have great potential as a healthy food, as they are rich in phenolic compounds with high antioxidant and anti-proliferative activities to cancer cells. |
eng |
dc.language.iso |
eng |
|
dc.publisher |
Amsterdam : Elsevier B.V. |
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dc.relation.ispartofseries |
Horticultural Plant Journal 5 (2019), Nr. 4 |
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dc.rights |
CC BY-NC-ND 4.0 Unported |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
dc.subject |
Anti-proliferative activity |
eng |
dc.subject |
Antioxidant activity |
eng |
dc.subject |
Crabapple |
eng |
dc.subject |
Human cancer cell |
eng |
dc.subject |
Phenolic profile |
eng |
dc.subject.ddc |
630 | Landwirtschaft, Veterinärmedizin
|
ger |
dc.title |
Phenolic Profile, Antioxidant Activity and Anti-proliferative Activity of Crabapple Fruits |
|
dc.type |
Article |
|
dc.type |
Text |
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dc.relation.issn |
2095-9885 |
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dc.relation.doi |
https://doi.org/10.1016/j.hpj.2019.01.003 |
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dc.bibliographicCitation.issue |
4 |
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dc.bibliographicCitation.volume |
5 |
|
dc.bibliographicCitation.firstPage |
155 |
|
dc.bibliographicCitation.lastPage |
163 |
|
dc.description.version |
publishedVersion |
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tib.accessRights |
frei zug�nglich |
|