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Auflistung Fakultäten nach Schlagwort "C-CPE"
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Alnajjar, Suhayla; Nolte, Ingo; Becker, Annegret; Schille, Jan Torben; Trakooljul, Nares; Frank, Marcus; Ngezahayo, Anaclet; Murua Escobar, Hugo
(Basel : Molecular Diversity Preservation International (MDPI), 2021)
Claudin (CLDN) proteins are commonly expressed in cancers and targeted in novel therapeutic approaches. The C-terminal of Clostridium perfringens enterotoxin (C-CPE) efficiently binds several claudins. In this study, ...
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Becker, Annegret; Leskau, Miriam; Schlingmann-Molina, Barbara L.; Hohmeier, Susanne C.; Alnajjar, Suhayla; Escobar, Hugo Murua; Ngezahayo, Anaclet
(London : Nature Publishing Group, 2018)
A recombinant produced C-terminus of the C. perfringens enterotoxin (C-CPE) was conjugated to gold nanoparticles (AuNPs) to produce a C-CPE-AuNP complex (C-CPE-AuNP). By binding to claudins, the C- CPE should allow to ...
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Becker, Annegret; Lehrich, Tina; Kalies, Stefan; Heisterkamp, Alexander; Ngezahayo, Anaclet
(Basel : MDPI AG, 2019)
Recently, we used a recombinant produced C-terminus (D194-F319) of the Clostridium perfringens enterotoxin (C-CPE) to functionalize gold nanoparticles (AuNPs) for a subsequent specific killing of claudin expressing tumor ...
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Riesenberg, Carolin; Iriarte-Valdez, Christian Alejandro; Becker, Annegret; Dienerowitz, Maria; Heisterkamp, Alexander; Ngezahayo, Anaclet; Torres-Mapa, Maria Leilani
(Lausanne : Frontiers Media, 2020)
This work probes the binding kinetics of COOH-terminus of Clostridium perfringens enterotoxin (c-CPE) and claudin expressing MCF-7 cells using force spectroscopy with optical tweezers. c-CPE is of high biomedical interest ...
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Becker, Annegret
(Hannover : Institutionelles Repositorium der Leibniz Universität Hannover, 2019)
Tight Junctions sind apikale interzelluläre Proteinverbindungen zwischen Epithelzellen. Die Überexpression von bestimmten Proteinen der Tight Junctions wie z.B. Claudin-3, -4 und -7 ist für einige Krebsarten charakteristisch. ...