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Ruffert, Christine: Magnetic bead-magic bullet. In: Micromachines 7 (2016), Nr. 2, 21. DOI: http://dx.doi.org/10.3390/mi7020021

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To cite the version in the repository, please use this identifier: https://doi.org/10.15488/749

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Sum total of downloads: 325




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Abstract: 
Microfluidics is assumed to be one of the leading and most promising areas of research since the early 1990s. In microfluidic systems, small spherical magnetic particles with superparamagnetic properties, called magnetic beads, play an important role in the design of innovative methods and tools, especially in bioanalysis and medical sciences. The intention of this review paper is to address main aspects from the state-of-the-art in the area of magnetic bead research, while demonstrating the broad variety of applications and the huge potential to solve fundamental biological and medical problems in the fields of diagnostics and therapy. Basic issues and demands related to the fabrication of magnetic particles and physical properties of nanosize magnets are discussed in Section 2. Of main interest are the control and adjustment of the nanoparticles’ properties and the availability of adequate approaches for particle detection via their magnetic field. Section 3 presents an overview of magnetic bead applications in nanomedicine. In Section 4, practical aspects of sample manipulation and separation employing magnetic beads are described. Finally, the benefits related to the use of magnetic bead-based microfluidic systems are summarized, illustrating ongoing questions and open tasks to be solved on the way to an approaching microfluidic age.
License of this version: CC BY-NC-SA 4.0
Document Type: article
Publishing status: publishedVersion
Issue Date: 2016
Appears in Collections:Fakultät für Maschinenbau

distribution of downloads over the selected time period:

downloads by country:

pos. country downloads
total perc.
1 image of flag of Germany Germany 182 56.00%
2 image of flag of France France 33 10.15%
3 image of flag of United States United States 31 9.54%
4 image of flag of Russian Federation Russian Federation 15 4.62%
5 image of flag of United Kingdom United Kingdom 12 3.69%
6 image of flag of Netherlands Netherlands 9 2.77%
7 image of flag of No geo information available No geo information available 4 1.23%
8 image of flag of Morocco Morocco 4 1.23%
9 image of flag of Italy Italy 3 0.92%
10 image of flag of Indonesia Indonesia 3 0.92%
    other countries 29 8.92%

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