Advances in the application of electrohydrodynamic fabrication for tissue engineering

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Gryshkov, O.; Müller, M.; Leal-Marin, S.; Mutsenko, V.; Suresh, S. et al.: Advances in the application of electrohydrodynamic fabrication for tissue engineering. In: Journal of Physics: Conference Series 1236 (2019), Nr. 1, 12024. DOI: https://doi.org/10.1088/1742-6596/1236/1/012024

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Abstract: 
Tissue engineering and cell-based therapy approaches require artificial scaffolds as extracellular matrix (ECM) and three-dimensional (3D) environment for clinically relevant cells to attach, be metabolically active and proliferate. Moreover, these constructs must possess mechanical and physical-chemical properties matched with certain implantation site. If all the required conditions are met, a tissue-engineered construct is considered as functional and will regenerate or replace the damaged tissue after implantation. In this work, we give a short overview of so-called electrohydrodynamic approach (EHD), e.g. with an application of electric field, to fabricate nano- and microstructured porous polymeric networks. This includes the application of electrospinning (networks) and electrospraying (micro- and macrospheres) to produce scaffolds and semipermeable hydrogel structures as a basis for tissue engineering and cell-based therapies.
License of this version: CC BY 3.0
Document Type: article
Publishing status: publishedVersion
Issue Date: 2019
Appears in Collections:Fakultät für Maschinenbau

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1 image of flag of Germany Germany 15 93.75%
2 image of flag of India India 1 6.25%

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