p-BioSPRE-an information and communication technology framework for transnational biomaterial sharing and access

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Weiler, Gabriele; Schroder, Christina; Schera, Fatima; Dobkowicz, Matthias; Kiefer, Stephan et al.: p-BioSPRE-an information and communication technology framework for transnational biomaterial sharing and access. In: Ecancermedicalscience 8 (2014), 401. DOI: http://dx.doi.org/10.3332/ecancer.2014.401

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Sum total of downloads: 152

Biobanks represent key resources for clinico-genomic research and are needed to pave the way to personalised medicine. To achieve this goal, it is crucial that scientists can securely access and share high-quality biomaterial and related data. Therefore, there is a growing interest in integrating biobanks into larger biomedical information and communication technology (ICT) infrastructures. The European project p-medicine is currently building an innovative ICT infrastructure to meet this need. This platform provides tools and services for conducting research and clinical trials in personalised medicine. In this paper, we describe one of its main components, the biobank access framework p-BioSPRE (p-medicine Biospecimen Search and Project Request Engine). This generic framework enables and simplifies access to existing biobanks, but also to offer own biomaterial collections to research communities, and to manage biobank specimens and related clinical data over the ObTiMA Trial Biomaterial Manager. p-BioSPRE takes into consideration all relevant ethical and legal standards, e.g., safeguarding donors’ personal rights and enabling biobanks to keep control over the donated material and related data. The framework thus enables secure sharing of biomaterial within open and closed research communities, while flexibly integrating related clinical and omics data. Although the development of the framework is mainly driven by user scenarios from the cancer domain, in this case, acute lymphoblastic leukaemia and Wilms tumour, it can be extended to further disease entities.
License of this version: CC BY 3.0
Document Type: article
Publishing status: publishedVersion
Issue Date: 2014
Appears in Collections:Juristische Fakultät

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downloads by country:

pos. country downloads
total perc.
1 image of flag of Germany Germany 128 84.21%
2 image of flag of United States United States 4 2.63%
3 image of flag of Russian Federation Russian Federation 3 1.97%
4 image of flag of Romania Romania 2 1.32%
5 image of flag of Netherlands Netherlands 2 1.32%
6 image of flag of Indonesia Indonesia 2 1.32%
7 image of flag of Spain Spain 2 1.32%
8 image of flag of Algeria Algeria 2 1.32%
9 image of flag of Pakistan Pakistan 1 0.66%
10 image of flag of Czech Republic Czech Republic 1 0.66%
    other countries 5 3.29%

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