The paper presents a novel concept of solar thermal panel specifically intended for building integration, aiming at a higher architectural quality and at a reduction of installation costs. The panel consists of a low-emissivity enameled flat glass as solar absorber and a metallic heat exchanger, which are glued together by an adhesive layer. It features high design flexibility and can be used as roof or façade cladding in combination with common frames and profiles. We analyze the potential of the panel both as uncovered and covered collector by means of efficiency measurements on large-sized prototypes according to ISO 9806. Our results show that panels equipped with black enameled glass can achieve performance values competitive with those of commercial available products (uncovered panel: η0 = 0.75, b1 = 8.05 W/m2K, b2 = 1.64 J/m3K, bu = 0.043 s/m; covered panel: η0 = 0.74, a1 = 4.26 W/m2K, a2 = 0.013 W/m2K2). As reported by our optical measurements on small samples, colored glass can exhibit solar absorptance up to 0.93, thus representing an aesthetically appealing alternative to black panels. For its implementation, system integration, operating conditions and design aspects have to be taken into consideration.