Ludwig, K.; Graf von der Schulenburg, J.-M.; Greiner, W.: German Value Set for the EQ-5D-5L. In: PharmacoEconomics 2018 (2018), 1-12. DOI: https://doi.org/10.1007/s40273-018-0615-8
Zusammenfassung: | |
Objectives: The objective of this study was to develop a value set for EQ-5D-5L based on the societal preferences of the German population. As the first country to do so, the study design used the improved EQ-5D-5L valuation protocol 2.0 developed by the EuroQol Group, including a feedback module as internal validation and a quality control process that was missing in the first wave of EQ-5D-5L valuation studies. Methods: A representative sample of the general German population (n = 1158) was interviewed using a composite time trade-off and a discrete choice experiment under close quality control. Econometric modeling was used to estimate values for all 3125 possible health states described by EQ-5D-5L. The value set was based on a hybrid model including all available information from the composite time trade-off and discrete choice experiment valuations without any exclusions due to data issues. Results: The final German value set was constructed from a combination of a conditional logit model for the discrete choice experiment data and a censored at −1 Tobit model for the composite time trade-off data, correcting for heteroskedasticity. The value set had logically consistent parameter estimates (p < 0.001 for all coefficients). The predicted EQ-5D-5L index values ranged from −0.661 to 1. Conclusions: This study provided values for the health states of the German version of EQ-5D-5L representing the preferences of the German population. The study successfully employed for the first time worldwide the improved protocol 2.0. The value set enables the use of the EQ-5D-5L instrument in economic evaluations and in clinical studies. © 2018 The Author(s) | |
Lizenzbestimmungen: | CC BY-NC 4.0 Unported |
Publikationstyp: | Article |
Publikationsstatus: | publishedVersion |
Erstveröffentlichung: | 2018 |
Die Publikation erscheint in Sammlung(en): | Wirtschaftswissenschaftliche Fakultät |
Pos. | Land | Downloads | ||
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Anzahl | Proz. | |||
1 | Germany | 680 | 75,06% | |
2 | United States | 48 | 5,30% | |
3 | Austria | 37 | 4,08% | |
4 | Switzerland | 32 | 3,53% | |
5 | No geo information available | 15 | 1,66% | |
6 | Russian Federation | 10 | 1,10% | |
7 | Iran, Islamic Republic of | 7 | 0,77% | |
8 | Indonesia | 7 | 0,77% | |
9 | United Kingdom | 7 | 0,77% | |
10 | Czech Republic | 5 | 0,55% | |
andere | 58 | 6,40% |
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