In this report, we will give the first constraints on in-matter nonmetricity. We will show how the effective-field-theory (EFT) toolbox developed for the study of Lorentz violation (LV) can be employed for investigations of the "effective LV" background caused by nonmetricity, a geometric object extending the notion of a Riemannian manifold. The idea is to probe for the effects of spacetime nonmetricity sourced by liquid 4He with polarized slow neutrons. We present the first constraints on isotropic and parity-odd nonmetricity components. Further constraints on anisotropic nonmetricity components within this EFT framework may be feasible with proper experimental techniques in the near future. © Published under licence by IOP Publishing Ltd.