Optimization of a test setup for examining blood damage caused by high shear forces

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Kortlepel, R.; Krolitzki, B.; Müller, M.; Glasmacher, Birgit: Optimization of a test setup for examining blood damage caused by high shear forces. In: Biomedical Engineering / Biomedizinische Technik 57 (2012), Nr. SI-1 Track-D. DOI: http://dx.doi.org/10.1515/bmt-2012-4362

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Sum total of downloads: 155




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Abstract: 
If blood pumps are applied in the human body or extracorporeal, blood damage can be caused by shear forces that act on the blood during the delivery. For an accelerated development of blood pumps with help of simulations there is a need for reliable limit values for shear forces. To determine these limit values a shear force test setup was built at the Institute for Multiphase Processes. In the context of the presented master thesis the former test setup peripheral devices were evaluated, possible blood damage mechanisms were considered, blood analysis in different experiments to identify the blood damage caused by different elements were made and peripheral devices were replaced. At the same time the shear chamber was constructional reengineered in a project thesis [1]. We were able to show, that in former works the blood damage caused by test setup peripheral devices had heterodyned the results. Finally the test setup was rebuilt with the results and a test was made. Two findings of the thesis are a reduction of about 60% of the number of components in the blood-conveying tube system and an application of a new fluid seal.
License of this version: Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden. Dieser Beitrag ist aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.
Document Type: article
Publishing status: publishedVersion
Issue Date: 2012-08-27
Appears in Collections:Naturwissenschaftliche Fakultät

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pos. country downloads
total perc.
1 image of flag of Germany Germany 124 80.00%
2 image of flag of United States United States 14 9.03%
3 image of flag of China China 6 3.87%
4 image of flag of Russian Federation Russian Federation 3 1.94%
5 image of flag of Ukraine Ukraine 1 0.65%
6 image of flag of Qatar Qatar 1 0.65%
7 image of flag of India India 1 0.65%
8 image of flag of Hungary Hungary 1 0.65%
9 image of flag of Brazil Brazil 1 0.65%
10 image of flag of Bangladesh Bangladesh 1 0.65%
    other countries 2 1.29%

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