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Download statistics - Document (COUNTER):
Chen, W.; Chen, R.; Liu, Q.; He, Y.; He, K. et al.: Orange, red, yellow: Biosynthesis of azaphilone pigments in Monascus fungi. In: Chemical Science 8 (2017), Nr. 7, S. 4917-4925. DOI: https://doi.org/10.1039/c7sc00475c
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Sum total of downloads: 294
| Abstract: | |
Monascus azaphilone pigments (MonAzPs) are very widely used as food colorants, but their biosynthetic pathway has remained poorly characterized for more than half a century. In this study, the individual steps of MonAzPs biosynthesis in Monascus ruber M7 were elucidated by a combination of targeted gene knockouts, heterologous gene expression, and in vitro chemical and enzymatic reactions. This study describes the first rational engineering of MonAzPs biosynthesis and provides a roadmap for future pathway engineering efforts directed towards the selective production of the most valuable pigments and serves as a model for the biosynthesis of fungal azaphilones in general. | |
| License of this version: | CC BY-NC 3.0 Unported |
| Document Type: | Article |
| Publishing status: | publishedVersion |
| Issue Date: | 2017 |
| Appears in Collections: | Naturwissenschaftliche Fakultät |
distribution of downloads over the selected time period:
downloads by country:
| pos. | country | downloads | ||
|---|---|---|---|---|
| total | perc. | |||
| 1 |  |
Germany | 124 | 42.18% |
| 2 |  |
United States | 76 | 25.85% |
| 3 |  |
China | 32 | 10.88% |
| 4 |  |
No geo information available | 7 | 2.38% |
| 5 |  |
Japan | 7 | 2.38% |
| 6 |  |
Italy | 5 | 1.70% |
| 7 |  |
France | 5 | 1.70% |
| 8 |  |
Taiwan | 4 | 1.36% |
| 9 |  |
Poland | 3 | 1.02% |
| 10 |  |
Ireland | 3 | 1.02% |
| other countries | 28 | 9.52% | ||
Further download figures and rankings:
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