High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar

Download statistics - Document (COUNTER):

Schlottmann, F.; Kirk, A.T.; Allers, M.; Bohnhorst, A.; Zimmermann, S.: High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar. In: Journal of the American Society for Mass Spectrometry : JASMS online 31 (2020), Nr. 7, S. 1536-1543. DOI: https://doi.org/10.1021/jasms.0c00098

Repository version

To cite the version in the repository, please use this identifier: https://doi.org/10.15488/10990

Selected time period:


Sum total of downloads: 22

High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) are usually operated at an absolute pressure of 20 mbar reaching high reduced electric field strengths of up to 125 Td for controlled reaction kinetics. This significantly increases the linear range and limits chemical cross sensitivities. Furthermore, HiKE-IMS enables the ionization of compounds normally not detectable in ambient pressure IMS, such as benzene, due to new reaction pathways and the inhibition of clustering reactions. In addition, HiKE-IMS allows the observation of additional orthogonal parameters related to an increased ion temperature such as fragmentation and field-dependent ion mobility, which may help to separate compounds that have similar ion mobility under low field conditions.Aiming for a hand-held HiKE-IMS to carry its benefits into field applications, reducing size and power consumption of the vacuum system is necessary. In this work, we present a novel HiKE-IMS design entirely manufactured from standard printed circuit boards (PCB) and experimentally investigate the analytical performance in dependence of the operating pressure between 20 mbar and 40 mbar. Hereby, the limit of detection (LoD) for benzene in purified, dry air (1.4 ppmV water) improved from 7 ppbV at 20 mbar down to 1.8 ppbV at 40 mbar. Furthermore, adding 0.9 ppmV toluene the signal of the benzene B+ peak decreases by only 2 % at 40 mbar. Even in the presence of high relative humidity in the sample gas above 90 % or toluene concentrations of up to 20 ppmV, the LoD for benzene just increases to 9 ppbV at 40 mbar.
License of this version: Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden.
Document Type: article
Publishing status: acceptedVersion
Issue Date: 2020
Appears in Collections:Fakultät für Elektrotechnik und Informatik

distribution of downloads over the selected time period:

downloads by country:

pos. country downloads
total perc.
1 image of flag of Germany Germany 20 90.91%
2 image of flag of United States United States 1 4.55%
3 image of flag of China China 1 4.55%

Further download figures and rankings:


Zur Erhebung der Downloadstatistiken kommen entsprechend dem „COUNTER Code of Practice for e-Resources“ international anerkannte Regeln und Normen zur Anwendung. COUNTER ist eine internationale Non-Profit-Organisation, in der Bibliotheksverbände, Datenbankanbieter und Verlage gemeinsam an Standards zur Erhebung, Speicherung und Verarbeitung von Nutzungsdaten elektronischer Ressourcen arbeiten, welche so Objektivität und Vergleichbarkeit gewährleisten sollen. Es werden hierbei ausschließlich Zugriffe auf die entsprechenden Volltexte ausgewertet, keine Aufrufe der Website an sich.

Search the repository