Ultra-high-resolution ion mobility spectrometry : current instrumentation, limitations, and future developments

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Kirk, A.T.; Bohnhorst, A.; Raddatz, C.-R.; Allers, M.; Zimmermann, S.: Ultra-high-resolution ion mobility spectrometry : current instrumentation, limitations, and future developments. In: Analytical and bioanalytical chemistry 411 (2019), S. 6229-6246. DOI: https://doi.org/10.1007/s00216-019-01807-0

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Sum total of downloads: 487




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Abstract: 
With recent advances in ionization sources and instrumentation, ion mobility spectrometers (IMS) have transformed from a detector for chemical warfare agents and explosives to a widely used tool in analytical and bioanalytical applications. This increasing measurement task complexity requires higher and higher analytical performance and especially ultra-high resolution. In this review, we will discuss the currently used ion mobility spectrometers able to reach such ultra-high resolution, defined here as a resolving power greater than 200. These instruments are drift tube IMS, traveling wave IMS, trapped IMS, and field asymmetric or differential IMS. The basic operating principles and the resulting effects of experimental parameters on resolving power are explained and compared between the different instruments. This allows understanding the current limitations of resolving power and how ion mobility spectrometers may progress in the future.
License of this version: Es gilt deutsches Urheberrecht. Das Dokument darf zum eigenen Gebrauch kostenfrei genutzt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden.
Document Type: Article
Publishing status: acceptedVersion
Issue Date: 2019
Appears in Collections:Fakultät für Elektrotechnik und Informatik

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pos. country downloads
total perc.
1 image of flag of Germany Germany 182 37.37%
2 image of flag of United States United States 81 16.63%
3 image of flag of Russian Federation Russian Federation 38 7.80%
4 image of flag of China China 20 4.11%
5 image of flag of India India 15 3.08%
6 image of flag of France France 14 2.87%
7 image of flag of Belgium Belgium 11 2.26%
8 image of flag of No geo information available No geo information available 9 1.85%
9 image of flag of Iran, Islamic Republic of Iran, Islamic Republic of 9 1.85%
10 image of flag of Canada Canada 8 1.64%
    other countries 100 20.53%

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