Voges, J.; Paridaens, T.; Müntefering, F.; Mainzer, L.S.; Bliss, B. et al.: GABAC : An arithmetic coding solution for genomic data. In: Bioinformatics 36 (2020), Nr. 7, S. 2275-2277. DOI: https://doi.org/10.1093/bioinformatics/btz922
Abstract: | |
Motivation: In an effort to provide a response to the ever-expanding generation of genomic data, the International Organization for Standardization (ISO) is designing a new solution for the representation, compression and management of genomic sequencing data: the Moving Picture Experts Group (MPEG)-G standard. This paper discusses the first implementation of an MPEG-G compliant entropy codec: GABAC. GABAC combines proven coding technologies, such as context-adaptive binary arithmetic coding, binarization schemes and transformations, into a straightforward solution for the compression of sequencing data. Results: We demonstrate that GABAC outperforms well-established (entropy) codecs in a significant set of cases and thus can serve as an extension for existing genomic compression solutions, such as CRAM. © 2019 The Author(s). Published by Oxford University Press. | |
License of this version: | CC BY-NC 4.0 Unported |
Document Type: | Article |
Publishing status: | publishedVersion |
Issue Date: | 2020 |
Appears in Collections: | Fakultät für Elektrotechnik und Informatik |
pos. | country | downloads | ||
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total | perc. | |||
1 | ![]() |
Germany | 83 | 66.40% |
2 | ![]() |
United States | 24 | 19.20% |
3 | ![]() |
China | 6 | 4.80% |
4 | ![]() |
Taiwan | 2 | 1.60% |
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Russian Federation | 2 | 1.60% |
6 | ![]() |
India | 2 | 1.60% |
7 | ![]() |
Japan | 1 | 0.80% |
8 | ![]() |
Israel | 1 | 0.80% |
9 | ![]() |
United Kingdom | 1 | 0.80% |
10 | ![]() |
United Arab Emirates | 1 | 0.80% |
other countries | 2 | 1.60% |
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