Development of a biodegradable microstent for minimally invasive treatment of Fallopian tube occlusions

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Dierke, A.; Borowski, F.; Großmann, S.; Brandt-Wunderlich, C.; Matschegewski, C. et al.: Development of a biodegradable microstent for minimally invasive treatment of Fallopian tube occlusions. In: Current Directions in Biomedical Engineering 6 (2020), Nr. 3, 20203019. DOI: https://doi.org/10.1515/cdbme-2020-3019

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Sum total of downloads: 156




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Abstract: 
Obstructions of the Fallopian tube represent one of the most common reasons for an unfulfilled desire to have children. Microstent technology opens up new therapeutic possibilities to restore the natural lumen of the Fallopian tube within a single treatment. Within the current work we developed a self-expandable biodegradable microstent for gynecological applications. Based on a novel microstent design, prototypes were manufactured from poly-L-lactide tubing by means of fs-laser cutting. Microstent prototypes were characterized morphologically by means of scanning electron microscopy and biaxial laser scanning. As manufactured, a microstents outside diameter of about 2.3 mm and a strut thickness/width of about 114 µm/103 µm was measured. Mechanical characterization of microstents included bending as well as crimping and release behavior. After crimping to a minimum diameter of 0.8 mm and consecutive release, a microstent recovery to a diameter of 1.8 mm was found. Therefore, proof-of-concept for the self-expandable microstent could be successfully provided. © 2020 by Walter de Gruyter Berlin/Boston 2020.
License of this version: CC BY 4.0 Unported
Document Type: Article
Publishing status: publishedVersion
Issue Date: 2020
Appears in Collections:Fakultät für Mathematik und Physik

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pos. country downloads
total perc.
1 image of flag of Germany Germany 104 66.67%
2 image of flag of United States United States 24 15.38%
3 image of flag of China China 10 6.41%
4 image of flag of No geo information available No geo information available 4 2.56%
5 image of flag of Latvia Latvia 3 1.92%
6 image of flag of Sweden Sweden 2 1.28%
7 image of flag of Israel Israel 2 1.28%
8 image of flag of Switzerland Switzerland 2 1.28%
9 image of flag of United Kingdom United Kingdom 1 0.64%
10 image of flag of Czech Republic Czech Republic 1 0.64%
    other countries 3 1.92%

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