Simultaneous cancer control and diagnosis with magnetic nanohybrid materials

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Saadat, R.; Renz, F.: Simultaneous cancer control and diagnosis with magnetic nanohybrid materials. In: Beilstein Journal of Nanotechnology 7 (2016), Nr. 1, S. 121-125. DOI:

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Sum total of downloads: 98

Coated magnetite nanoparticles were linked to 68Ga complexes used in the positron emission tomography (PET) for a new technical approach to detect cancer tissue with radiopharmaceuticals. By substitution of the Ga isotope with an alpha emitter the same compound could be used for cancer treatment. Furthermore the nanoparticles were connected to pH-sensitive complexes, enabling a pH-controlled assembly/disassembly and therefore the spreading of the particles in the tissue. With this novel method of combining detection and treatment simultaneously, the amount of medical exposure could be minimized for the patient. The results demonstrate that magnetite nanoparticles can effectively be functionalized with PET isotopes and pH sensitive complexes in order to use them as a new type of radiopharmaceuticals. © 2016 Saadat and Renz.
License of this version: CC BY 2.0 Unported
Document Type: Text
Publishing status: publishedVersion
Issue Date: 2016
Appears in Collections:Naturwissenschaftliche Fakultät

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pos. country downloads
total perc.
1 image of flag of Germany Germany 83 84.69%
2 image of flag of France France 4 4.08%
3 image of flag of Vietnam Vietnam 2 2.04%
4 image of flag of Netherlands Netherlands 2 2.04%
5 image of flag of Venezuela Venezuela 1 1.02%
6 image of flag of United States United States 1 1.02%
7 image of flag of Iraq Iraq 1 1.02%
8 image of flag of Indonesia Indonesia 1 1.02%
9 image of flag of Costa Rica Costa Rica 1 1.02%
10 image of flag of Canada Canada 1 1.02%
    other countries 1 1.02%

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