Differential Inductive Sensor for Continuous Non-Invasive Cell Growth Monitoring in Disposable Bioreactors

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Allers, M.; Reinecke, T.; Nagraik, T.; Solle, D.; Bakes, K. et al.: Differential Inductive Sensor for Continuous Non-Invasive Cell Growth Monitoring in Disposable Bioreactors. In: Proceedings 1 (2017), Nr. 4, 518. DOI: https://doi.org/10.3390/proceedings1040518

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Sum total of downloads: 61

In this work, we present a low-cost sensor system for continuous non-invasive cell growth monitoring, especially for single use bioreactor (SUB) applications. The sensor system is based on a differential transformer. Using this differential setup, the influence of the primary magnetic flux is eliminated from the measuring signal, enabling highly sensitive non-invasive detection of permittivity changes in the culture medium. To evaluate the sensor, E. coli cultivations are performed and the cell density is measured through the polymer foil of a SUB. We found a linear dependency with low data scattering between measuring signal and cell density.
License of this version: CC BY 4.0 Unported
Document Type: Article
Publishing status: publishedVersion
Issue Date: 2017
Appears in Collections:Fakultät für Maschinenbau

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pos. country downloads
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1 image of flag of Germany Germany 38 62.30%
2 image of flag of United States United States 13 21.31%
3 image of flag of China China 4 6.56%
4 image of flag of Canada Canada 2 3.28%
5 image of flag of Taiwan Taiwan 1 1.64%
6 image of flag of Norway Norway 1 1.64%
7 image of flag of United Kingdom United Kingdom 1 1.64%
8 image of flag of France France 1 1.64%

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